Adrenic Acid (22:4, n-6) CAS: 28874-58-0
MF: C22H36O2
MW: 332.5
A polyunsaturated fatty acid believed to be a source of arachidonic acid.

Adrenic Acid (22:4, n-6) (CAS 28874-58-0)

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Synonym: cis-7,10,13,16-Docosatetraenoic acid
Application A polyunsaturated fatty acid believed to be a source of arachidonic acid
CAS 등록번호: 28874-58-0
순도: ≥96%
분자량: 332.5
분자식: C22H36O2
* 참조분석증명서대량의 측정 데이터(함수량포함).
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Adrenic Acid (22-4,n-6), also known as 7,10,13,16-Docosatetraenoic acid, is a polyunsaturated fatty acid. Peroximal β-oxidation of 7,10,13,16-docosatetraenoic acid has been shown to form arachidonic acid. Endothelial cells have been shown to convert arachidonic acid to docosatetraenoic acid and releasing docosatetraenoic acid when exposed to ionophore A23187 (sc-3591). Additionally, endothelial cell studies have demonstrated that adrenic acid reduces prostaglandin 12.


References

1. Campbell, W.B., et al. 1985. Biochim. Biophys. Acta. 837: 67-76. PMID: 3931686
2. Mann, C.J., et al. 1986. Arch. Biochem. Biophys. 244: 813-823. PMID: 3080955
3. Baykousheva, S.P., et al. 1994. J. Biol. Chem. 269: 18390-18394. PMID: 8034586
4. Krämer, S.D., et al. 2002. In Vitro Cell. Dev. Biol. Anim. 38: 566-571. PMID: 12762838
5. McNamara, R.K., et al. 2010. Eur J Pharmacol. [Epub ahead of print]. PMID: 21118685

Appearance :
Oil
Physical State :
Liquid
용해도 :
Soluble in ethanol, hexane, methylene chloride, DMSO (100 mg/ml), DMF (100 mg/ml), and PBS pH 7.4. Insoluble in water.
저장 :
Store at -20° C
비등점 :
439.49° C at 760 mmHg
밀도 :
0.92 g/mL
굴절률 :
n20D 1.50
연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.
WGK Germany :
3
PubChem CID :
5497181
MDL Number :
MFCD00673435
SMILES :
CCCCCC=CCC=CCC=CCC=CCCCCCC(=O)O

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Citations 1 to 1 of {3} total

PMID: # 21118685  McNamara, RK. et al. 2011. Eur. J. Pharmacol. 652: 152-156.

Citations 1 to 1 of {3} total
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