ACBD4 Antibody (G-8): sc-514694
- ACBD4 Antibody (G-8) is a mouse monoclonal IgG1 κ ACBD4 antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 126-152 within an internal region of ACBD4 of human origin
- ACBD4 Antibody (G-8) is recommended for detection of ACBD4 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-ACBD4 Antibody (G-8) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ACBD4 Antibody (G-8) for WB applications. These reagents are now offered in bundles with ACBD4 Antibody (G-8) (see ordering information below).
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ACBD4 Antibody (G-8) is a mouse monoclonal IgG1 kappa light chain antibody that detects ACBD4 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-ACBD4 antibody (G-8) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. The acyl-CoA-binding domain-containing protein 4 (ACBD4) is a crucial 268 amino acid protein characterized by a single acyl-CoA-binding domain, which plays a significant role in lipid metabolism and cellular signaling. ACBD4 is primarily located in the cytoplasm and is involved in the transport and metabolism of acyl-CoA esters, which are essential for fatty acid oxidation and energy production. Proper functioning of ACBD4 is vital for maintaining cellular energy homeostasis, and dysregulation has been implicated in various metabolic disorders and diseases. ACBD4 exists in three isoforms due to alternative splicing, which may contribute to functional diversity and regulatory mechanisms within different tissues. The gene encoding ACBD4 is located on human chromosome 17, a region that is also home to important tumor suppressor genes such as p53 and BRCA1, highlighting potential significance in cancer biology and metabolic regulation.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
ACBD4 Antibody (G-8) References:
- Birt-Hogg-Dubé Syndrome. | Welsch, MJ., et al. 2005. Int J Dermatol. 44: 668-73. PMID: 16101870
- BLIMP1 regulates cell growth through repression of p53 transcription. | Yan, J., et al. 2007. Proc Natl Acad Sci U S A. 104: 1841-6. PMID: 17264218
- Neurofibromatosis 1, and Not TP53, seems to be the main target of chromosome 17 deletions in de novo acute myeloid leukemia. | Suela, J., et al. 2007. J Clin Oncol. 25: 1151-2; author reply 1152-3. PMID: 17369586
- Quantification of N-acetylaspartic acid in urine by LC-MS/MS for the diagnosis of Canavan disease. | Al-Dirbashi, OY., et al. 2007. J Inherit Metab Dis. 30: 612. PMID: 17632691
- Susceptibility to breast cancer: hereditary syndromes and low penetrance genes. | Nusbaum, R., et al. Breast Dis. 27: 21-50. PMID: 17917139
- Genetic causes of brain tumors: neurofibromatosis, tuberous sclerosis, von Hippel-Lindau, and other syndromes. | Farrell, CJ. and Plotkin, SR. 2007. Neurol Clin. 25: 925-46, viii. PMID: 17964021
- Breast cancer risk among male BRCA1 and BRCA2 mutation carriers. | Tai, YC., et al. 2007. J Natl Cancer Inst. 99: 1811-4. PMID: 18042939
- Novel deletion mutation in GFAP gene in an infantile form of Alexander disease. | Murakami, N., et al. 2008. Pediatr Neurol. 38: 50-2. PMID: 18054694
- Strategies for ovarian cancer prevention. | Dann, RB., et al. 2007. Obstet Gynecol Clin North Am. 34: 667-86, viii. PMID: 18061863
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ACBD4 Antibody (G-8) | sc-514694 | 200 µg/ml | $322.00 | |||
ACBD4 Antibody (G-8): m-IgG Fc BP-HRP Bundle | sc-531194 | 200 µg Ab; 10 µg BP | $361.00 | |||
ACBD4 Antibody (G-8): m-IgGκ BP-HRP Bundle | sc-524815 | 200 µg Ab, 40 µg BP | $361.00 | |||
ACBD4 Antibody (G-8) AC | sc-514694 AC | 500 µg/ml, 25% agarose | $424.00 | |||
ACBD4 Antibody (G-8) HRP | sc-514694 HRP | 200 µg/ml | $322.00 | |||
ACBD4 Antibody (G-8) FITC | sc-514694 FITC | 200 µg/ml | $336.00 | |||
ACBD4 Antibody (G-8) PE | sc-514694 PE | 200 µg/ml | $349.00 | |||
ACBD4 Antibody (G-8) Alexa Fluor® 488 | sc-514694 AF488 | 200 µg/ml | $364.00 | |||
ACBD4 Antibody (G-8) Alexa Fluor® 546 | sc-514694 AF546 | 200 µg/ml | $364.00 | |||
ACBD4 Antibody (G-8) Alexa Fluor® 594 | sc-514694 AF594 | 200 µg/ml | $364.00 | |||
ACBD4 Antibody (G-8) Alexa Fluor® 647 | sc-514694 AF647 | 200 µg/ml | $364.00 | |||
ACBD4 Antibody (G-8) Alexa Fluor® 680 | sc-514694 AF680 | 200 µg/ml | $364.00 | |||
ACBD4 Antibody (G-8) Alexa Fluor® 790 | sc-514694 AF790 | 200 µg/ml | $364.00 | |||
ACBD4 (G-8) Neutralizing Peptide | sc-514694 P | 100 µg/0.5 ml | $69.00 |