7Z,10Z,13Z,16Z,19Z-Docosapentaenoic acid CAS: 24880-45-3
MF: C22H34O2
MW: 330.50
A fatty acid shown to inhibit platelet aggregation.

7Z,10Z,13Z,16Z,19Z-Docosapentaenoic acid (CAS 24880-45-3)

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Synonym: Docosapentaenoic acid
Application A fatty acid shown to inhibit platelet aggregation
CAS 등록번호: 24880-45-3
순도: ≥98%
분자량: 330.50
분자식: C22H34O2
* 참조분석증명서대량의 측정 데이터(함수량포함).
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Docosa-7Z,10Z,13Z,16Z,19Z-pentaenoic Acid (22:5, n-3), also known as DPA, is a fatty acid derived from fish oils that potently inhibits platelet aggregation. DPA has been reported to block the cyclooxygenase pathway and stimulate the lipoxygenase pathway, which results in effective platelet aggregation inhibition. Peripheral blood mononuclear cell research demonstrates that DPA diminishes cyclooxygenase-2 levels intracellularly and inhibits pro-inflammatory prostaglandin E2 production. Studies indicate that the compound plays an important role in the cubic membrane formation of mitochondria found in amoeba Chaos.


1. Akiba, S., et al. 2000. Biol. Pharm. Bull. 23: 1293-1297. PMID: 11085354
2. Rissanen, T., et al. 2000. Circulation. 102: 2677-2679. PMID: 11094031
3. Deng, Y., et al. 2009. FASEB J. 23: 2866-2871. PMID: 19406841
4. Nauroth, J.M., et al. 2010. Lipids. 45: 375-384. PMID: 20364438
5. Kaur, G., et al. 2011. Prog. Lipid Res. 50: 28-34. PMID: 20655949

Appearance :
Physical State :
용해도 :
Soluble in ethanol, hexane, methylene chloride, 0.1M Na2CO3 (1.7 mg/ml), water (1.7 mg/ml) at 25° C, DMSO (~100 mg/ml), and DMF (~100 mg/ml).
저장 :
Store at -20° C
굴절률 :
n20D 1.51
IC50 :
Cytochrome P450 19A1: IC50 = 16.8 µM (human)
pK Values :
pKa: 4.76
연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.
WGK Germany :
PubChem CID :
MDL Number :



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