4-Aminosalicylic acid (CAS 65-49-6)

건강 상태 :

Solid

용해도 :

Soluble in water (2 g/l) at 20° C, dilute sodium hydroxide, dilute nitric acid, ether (slightly), methanol, acetone, and ethanol (1 G SOL IN 21 ML ALC). Virtually insoluble in benzene, chloroform, and carbon tetrachloride.

저장 :

Store at 4° C

녹는점 :

135-145° C (dec.)

비등점 :

380.76° C at 760 mmHg (Predicted)

밀도 :

1.49 g/cm³ (Predicted)

굴절률 :

n²⁰_D 1.69 (Predicted)

IC50 :

Estrogen receptor beta: IC₅₀ = 13.72 µM (human); Carbonic anhydrase I: IC₅₀ = 130 µM (human); Carbonic anhydrase II: IC₅₀ = 750 µM (human); Mycobacterium tuberculosis H37Rv: IC₅₀ >195 nM

Ki 데이타 :

Carbonic anhydrase I: K_i= 240 µM (human); Carbonic anhydrase II: K_i= 1230 µM (human)

pK 값 :

pK_a: 3.58 (Predicted), 3.25, pK_b: 2.21 (Predicted)

WGK 독일 :

2

RTECS :

VO1225000

PubChem CID :

Merck 색인 :

14: 477

MDL 번호 :

MFCD00007789

EC 번호 :

200-613-5

Beilstein 기재 :

473071

SMILES :

C1=CC(=C(C=C1N)O)C(=O)O