Date published: 2026-6-5

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2-(2-Hydroxy-1,1,1,3,3,3-hexafluoropropyl)-1-naphthol (CAS 2092-87-7)

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CAS Number:
2092-87-7
Molecular Weight:
310.2
Molecular Formula:
C13H8F6O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-(2-Hydroxy-1,1,1,3,3,3-hexafluoropropyl)-1-naphthol, known as HFN, is a fluorinated phenol derivative that holds immense significance in scientific research. This compound serves as a valuable reagent, thanks to its distinctive properties such as low toxicity and the capacity to form stable complexes with other molecules. 2-(2-Hydroxy-1,1,1,3,3,3-hexafluoropropyl)-1-naphthol has found utility as a reagent for synthesizing novel molecules, acting as a catalyst in organic reactions, and aiding the study of enzyme-substrate interactions. Moreover, it has been used to explore the structure and function of proteins and facilitating the detection of small molecules. The mechanism of action of 2-(2-Hydroxy-1,1,1,3,3,3-hexafluoropropyl)-1-naphthol revolves around its ability to form stable complexes with other molecules, a result of its unique structure that encompasses both a hydroxyl group and a fluorinated group. The hydroxyl group possesses the capability to engage in hydrogen bonding with other molecules, while the fluorinated group facilitates strong non-covalent interactions. These characteristics enable 2-(2-Hydroxy-1,1,1,3,3,3-hexafluoropropyl)-1-naphthol to establish robust and enduring complexes with other molecules, thus facilitating comprehensive studies on their structure and function.


2-(2-Hydroxy-1,1,1,3,3,3-hexafluoropropyl)-1-naphthol (CAS 2092-87-7) References

  1. Wireless gas detection with a smartphone via rf communication.  |  Azzarelli, JM., et al. 2014. Proc Natl Acad Sci U S A. 111: 18162-6. PMID: 25489066

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-(2-Hydroxy-1,1,1,3,3,3-hexafluoropropyl)-1-naphthol, 1 g

sc-304721
1 g
$145.00

2-(2-Hydroxy-1,1,1,3,3,3-hexafluoropropyl)-1-naphthol, 5 g

sc-304721A
5 g
$340.00