1-Methyl-4-(2prime-methylphenyl)-1,2,3,6-tetrahydropyridine hydrochloride CAS: 102417-86-7
MF: C13H17N•HCl
MW: 223.74
A dopaminergic neurotoxin.

1-Methyl-4-(2′-methylphenyl)-1,2,3,6-tetrahydropyridine hydrochloride (CAS 102417-86-7)

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Alternate Names: 2′-Methyl-MPTP hydrochloride
CAS 등록번호: 102417-86-7
분자량: 223.74
분자식: C13H17N•HCl
추가 정보: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.
* Refer to Certificate of Analysis for lot specific data (including water content).
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1-Methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine hydrochloride is a dopaminergic neurotoxin displaying higher toxicity than MPTP in mice.


References

Sonsalla, et al., Characteristics of 1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine-induced neurotoxicity in the mouse. J. Pharmacol. Exp. Ther. 242, 850, (1987) Youngster, et al., Evaluation of the biological activity of several analogs of the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. J. Neurochem. 48, 929, (1987) Youngster, et al., 1-Methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine (2'-CH-MPTP) is a more potent dopaminergic neurotoxin than MPTP in mice. Eur. J. Pharmacol. 122, 283, (1986)

Physical State :
Solid
용해도 :
H2O: soluble: ethanol: soluble
저장 :
Store at room temperature
녹는점 :
225-228° C
연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.
Transport :
UN 2811, Class 6.1, Packing group II
PubChem CID :
SMILES :
CC1=CC=CC=C1C2=CCN(CC2)C.Cl

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