YIC-C8-434 (CAS 214265-97-1)
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YIC-C8-434 is primarily used in chemical research focusing on the study of lipid interactions and membrane dynamics. This compound is instrumental in exploring the role of lipids in cellular processes such as vesicle formation, fusion, and transport. Researchers employ YIC-C8-434 to investigate the mechanisms of lipid bilayer disruption and the subsequent effects on cell viability and function. Additionally, it is used in the study of lipid-based chemical delivery systems, where understanding the interactions at the molecular level can enhance the efficiency and targeting capabilities of such systems. YIC-C8-434 also contributes to the field of biochemistry by aiding in the elucidation of pathways involved in lipid metabolism and signaling.
YIC-C8-434 (CAS 214265-97-1) References
- Structure-activity relationships of N-(3,5-dimethoxy-4-n-octyloxycinnamoyl)-N'-(3,4-dimethylphenyl)piperazine and analogues as inhibitors of acyl-CoA: cholesterol O-acyltransferase. | Ohishi, K., et al. 2001. Chem Pharm Bull (Tokyo). 49: 830-9. PMID: 11456087
- Sex-dependent toxicity of a novel acyl-CoA:cholesterol acyltransferase inhibitor, YIC-C8-434, in relation to sex-specific forms of cytochrome P450 in rats. | Kaneko, K., et al. 2001. Toxicol Sci. 64: 259-68. PMID: 11719709
- Inhibitory effects of N-(3,5-dimethoxy-4-n-octyloxycinnamoyl)-N'-(3,4-dimethylphenyl)piperazine (YIC-C8-434), an acyl-CoA:cholesterol O-acyltransferase inhibitor, on cholesterol esterification in the intestine and liver. | Ohishi, K., et al. 2003. Biol Pharm Bull. 26: 1125-8. PMID: 12913263
- Cholesterol esterification reduces the neurotoxicity of prions. | Bate, C., et al. 2008. Neuropharmacology. 54: 1247-53. PMID: 18448139
- HPLC-FLD determination of NBD-cholesterol, its ester and other metabolites in cellular lipid extracts. | Cao, XZ., et al. 2013. Biomed Chromatogr. 27: 910-5. PMID: 23526237
- Modulation of triglyceride and cholesterol ester synthesis impairs assembly of infectious hepatitis C virus. | Liefhebber, JM., et al. 2014. J Biol Chem. 289: 21276-88. PMID: 24917668
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
YIC-C8-434, 5 mg | sc-216068 | 5 mg | $245.00 |