Virginiamycin S1 CAS: 23152-29-6
MF: C43H49N7O10
MW: 823.89
A main component of virginiamycin preparations.

Virginiamycin S1 (CAS 23152-29-6)

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別名: Staphylomycin S,
アプリケーション: Virginiamycin S1 is a main component of virginiamycin preparations
CAS 番号: 23152-29-6
Purity: ≥99%
Molecular Weight: 823.89
Molecular Formula: C43H49N7O10
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* Refer to Certificate of Analysis for lot specific data (including water content).
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Virginiamycin S1 is a streptogramin antibiotic and one of the major active natural product components of Streptomyces virginiae antibiotic secretions. Virginiamycin S1 and virginiamycin M1 work synergistically to produce bacteriocidal action (see Virginiamycin complex, sc-202383), inhibiting protein synthesis of the target in an irreversible fashion upon exposure to both compounds.


参考文献

1. Crooy, P., et al. 1972. J. Antibiot. 25: 371-372. PMID: 4568014
2. Ogata, K., et al. 1978. J. Antibiot. 31: 1313-1315. PMID: 162634
3. Parfait, R., et al. 1980. Proc. Natl. Acad. Sci. U.S.A. 77: 5492-5496. PMID: 6776538
4. Reed, J.W., et al. 1986. J. Nat. Prod. 49: 626-630. PMID: 3097264
5. Prikrylová, V., et al. 1992. Folia Microbiol. 37: 386-388. PMID: 1493906
6. Namwat, W., et al. 2002. J. Bacteriol. 184: 4811-4818. PMID: 12169606

Physical State :
Solid
Derived From :
Streptomyces sp.
Solubility :
Soluble in ethanol, methanol, DMSO, DMF, and water (limited).
保存方法 :
Store at -20° C
Melting Point :
240-242° C
Boiling Point :
~1182.9° C at 760 mmHg (Predicted)
Density :
~1.4 g/cm3 (Predicted)
Refractive Index :
n20D 1.65 (Predicted)
pK Values :
pKa: 3.52 (Predicted), pKb: 5.11 (Predicted)
試験・研究用以外には使用しないでください。 臨床及び体外診断には使用できません。
WGK Germany :
3
PubChem CID :
Merck Index :
14: 10004
EC Number :
245-462-6
SMILES :
CC[[email protected]@H]1C(=O)N2CCC[[email protected]]2C(=O)N([[email protected]](C(=O)N3CCC(=O)C[[email protected]]3C(=O)N[[email protected]](C(=O)O[[email protected]@H]([[email protected]@H](C(=O)N1)NC(=O)C4=C(C=CC=N4)O)C)C5=CC=CC=C5)CC6=CC=CC=C6)C

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