STF 31 CAS: 724741-75-7
MF: C23H25N3O3S
MW: 423.53
A Glut1 and glucose uptake inhibitor.

STF 31 (CAS 724741-75-7)

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別名: 4-[[[[4-(1,1-Dimethylethyl)phenyl]s-ulfonyl]amino]methyl]-N-3-pyridinylbenzamide
アプリケーション: STF 31 is a Glut1 and glucose uptake inhibitor
CAS 番号: 724741-75-7
Purity: ≥99%
Molecular Weight: 423.53
Molecular Formula: C23H25N3O3S
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* Refer to Certificate of Analysis for lot specific data (including water content).
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STF 31 is a Glut1 inhibitor and a glucose uptake inhibitor in RCC (renal cell carcinoma) 4 cells. By limiting glucose uptake in cancer cells, the immense energy requirements for the cancer cell is not met and the cell does not have the resources to rapidly proliferate.


参考文献

1. Chan, Denise A., et al., 2011. Targeting GLUT1 and the Warburg effect in renal cell carcinoma by chemical synthetic lethality. Science translational medicine. 3(94): 94ra70. PMID: 21813754

Physical State :
Solid
Solubility :
Soluble in DMSO (>100 mM). Insoluble in water.
保存方法 :
Store at room temperature
Melting Point :
210° C
Density :
~1.2 g/cm3 (Predicted)
Refractive Index :
n20D 1.61 (Predicted)
試験・研究用以外には使用しないでください。 臨床及び体外診断には使用できません。
PubChem CID :
SMILES :
CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)NCC2=CC=C(C=C2)C(=O)NC3=CN=CC=C3

Download SDS (MSDS)

分析表

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STF 31 (CAS 724741-75-7)  参考文献

他の人がSTF 31 (CAS 724741-75-7)をどのように使用したかをご覧ください。 エントリをクリックして、PubMedエントリを表示します。 .

引用 1 to 3 of 3 合計

PMID: # 32699039  Renaudin, F.|Orliaguet, L.|Castelli, F.|Fenaille, F.|Prignon, A.|Alzaid, F.|Combes, C.|Delvaux, A.|Adimy, Y.|Cohen-Solal, M.|Richette, P.|Bardin, T.|Riveline, JP.|Venteclef, N.|Lioté, F.|Campillo-Gimenez, L.|Ea, HK.| et al. 2020. Ann Rheum Dis. 79: 1506-1514.

PMID: # 29849567  Cheng, XT.|Yang, FB.|Jiang, QQ.|Zhang, R.|Yang, SM.|Yu, N.| et al. 2018. Neural Plast. 2018: 7513217.

PMID: # 30464343  2018. Nature. 563: 714-718.

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