Stearoyl-L-carnitine-d3 Hydrochloride (CAS 32350-57-5 (unlabeled))
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Stearoyl-L-carnitine-d3 Hydrochloride, a deuterated derivative of stearoyl-L-carnitine, is primarily used in research to study lipid metabolism and mitochondrial fatty acid transport. The incorporation of deuterium allows for the tracing and analysis of stearoyl-L-carnitine metabolism using mass spectrometry, providing insights into its role and kinetics within biological systems. It serves as a tool to understand the function of carnitine palmitoyltransferase (CPT) enzymes that are critical for the transport of long-chain fatty acids into the mitochondria for β-oxidation. Additionally, Stearoyl-L-carnitine-d3 Hydrochloride is leveraged in research to explore the effects of altered lipid metabolism in various metabolic disorders. It also acts as an internal standard for the quantification of carnitine and its esters in metabolic studies, contributing to the accuracy and precision of analytical measurements.
Stearoyl-L-carnitine-d3 Hydrochloride (CAS 32350-57-5 (unlabeled)) References
- Matrix effect-corrected liquid chromatography/tandem mass-spectrometric method for determining acylcarnitines in human urine. | Abe, K., et al. 2017. Clin Chim Acta. 468: 187-194. PMID: 28274611
- Loss of Muscle Carnitine Palmitoyltransferase 2 Prevents Diet-Induced Obesity and Insulin Resistance despite Long-Chain Acylcarnitine Accumulation. | Pereyra, AS., et al. 2020. Cell Rep. 33: 108374. PMID: 33176143
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Stearoyl-L-carnitine-d3 Hydrochloride, 10 mg | sc-474409 | 10 mg | $350.00 |