Sodium dodecyl sulfate CAS: 151-21-3
Sodium dodecyl sulfate is an anionic detergent and protein denaturant.

Sodium dodecyl sulfate (CAS 151-21-3)

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別名: Sodium dodecyl sulfate is also known as SDS.
アプリケーション: Sodium dodecyl sulfate is an anionic detergent and protein denaturant
CAS 番号: 151-21-3
Purity: ≥96%
Molecular Weight: 288.38
Molecular Formula: C12H25O4S•Na
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
試験・研究用以外には使用しないでください。 臨床及び体外診断には使用できません。
* Refer to Certificate of Analysis for lot specific data (including water content).

Sodium dodecyl sulfate (SDS) is an anionic detergent used to solubilize and denature proteins in protein extraction and SDS-PAGE. Sodium dodecyl sulfate is useful in electrophoretic separation of proteins and lipids. Sodium dodecyl sulfate is also used in a variety of hybridization and molecular biology techniques. Sodium dodecyl sulfate is effective in both ionic and anionic conditions. Sodium dodecyl sulfate unravels proteins by binding to peptide chains and imparting a negative charge on the protein; this causes the protein to unfold eliminating shape as a factor for gel separation.

Also available in solution form: SDS (20% Solution) (sc-24950).


参考文献

1. Laemmli, U.K. 1970. Nature. 227(5259): 680-685. PMID: 5432063

2. Weber, K. and Kuter, D.J. 1971. J. Biol. Chem. 246(14): 4504-4509. PMID: 5106387

3. Harewood, K. and Wolff, J.S. 1973. Anal. Biochem. 55(2): 573-581. PMID: 4201521

4. Hayashi, K. 1975. Anal. Biochem. 67(2): 503-506. PMID: 1163770

5. Kapp, O.H. and Vinogradov, S.N. 1978. Anal. Biochem. 91(1): 230-235. PMID: 9762103

6. Womack, M.D. et al. 1983. Biochim. Biophys. Acta. 733(2): 210-215. PMID: 6882760

7. Grohs, R.A. et al. 1991. Anal. Chem. 63(4): 384-390. PMID: 1823727

8. Gallagher, S.R. 2007. Curr Protoc Cell Biol. Chapter6 : Unit 6.1. PMID: 18228518

Appearance :
Crystalline
Physical State :
Solid
Solubility :
Soluble in water (150 g/L at 20° C), and ethanol (partly soluble).
保存方法 :
Store at room temperature
Melting Point :
204-207° C (lit.)
IC50 :
Human HepG2/C3A cells: IC50 = 0.22 nM
Ki Data :
Displacement of C18-Aib-lucifer yellow from HIV1 envelope glycoprotein gp41 Fe(env2.0)3 receptor: Ki= 2000 nM
pK Values :
pKa: -3.29 (Predicted)
試験・研究用以外には使用しないでください。 臨床及び体外診断には使用できません。
WGK Germany :
2
RTECS :
WT1050000
PubChem CID :
3423265
Merck Index :
14: 8636
MDL Number :
MFCD00036175
EC Number :
205-788-1
Beilstein Registry :
3599286
SMILES :
CCCCCCCCCCCCOS(=O)(=O)[O-].[Na+]

Download SDS (MSDS)

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Sodium dodecyl sulfate (CAS 151-21-3)  参考文献

他の人がSodium dodecyl sulfate (CAS 151-21-3)をどのように使用したかをご覧ください。 エントリをクリックして、PubMedエントリを表示します。 .

引用 1 to 8 of 8 合計

PMID: # 26780454  Karimzadeh, F. et al. 2016. Mol. Neurobiol.

PMID: # 27038753  Aligholi, H. et al. 2016. Brain research. 1642: 197-208.

PMID: # 26141394  Wan, D. et al. 2015. Toxicol. Sci. 147: 326-38.

PMID: # 24962405  Ahn, JH. et al. 2014. J. Vet. Sci. 15: 335-42.

PMID: # 22393286  Akhtar, MJ. et al. 2012. Int J Nanomedicine. 7: 845-57.

PMID: # 22245848  Ahmad, J. et al. 2012. Toxicol. Appl. Pharmacol. 259: 160-8.

PMID: # 21606120  2011. Mol. Hum. Reprod. 17: 693-701.

PMID: # 28285257  Colloids Surf B Biointerfaces. 320-326.

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