Sodium dodecyl sulfate (CAS 151-21-3)

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別名: Sodium dodecyl sulfate is also known as SDS.

アプリケーション： Sodium dodecyl sulfate is an anionic detergent and protein denaturant

CAS 番号: 151-21-3

Purity: ≥96%

Molecular Weight: 288.38

Molecular Formula: C₁₂H₂₅O₄S•Na

Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.

試験・研究用以外には使用しないでください。臨床及び体外診断には使用できません。

* Refer to Certificate of Analysis for lot specific data (including water content).

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Sodium dodecyl sulfate (SDS) is an anionic detergent used to solubilize and denature proteins in protein extraction and SDS-PAGE. Sodium dodecyl sulfate is useful in electrophoretic separation of proteins and lipids. Sodium dodecyl sulfate is also used in a variety of hybridization and molecular biology techniques. Sodium dodecyl sulfate is effective in both ionic and anionic conditions. Sodium dodecyl sulfate unravels proteins by binding to peptide chains and imparting a negative charge on the protein; this causes the protein to unfold eliminating shape as a factor for gel separation.

Also available in solution form: SDS (20% Solution) (sc-24950).

参考文献

1. Laemmli, U.K. 1970. Nature. 227(5259): 680-685. PMID: 5432063

2. Weber, K. and Kuter, D.J. 1971. J. Biol. Chem. 246(14): 4504-4509. PMID: 5106387

3. Harewood, K. and Wolff, J.S. 1973. Anal. Biochem. 55(2): 573-581. PMID: 4201521

4. Hayashi, K. 1975. Anal. Biochem. 67(2): 503-506. PMID: 1163770

5. Kapp, O.H. and Vinogradov, S.N. 1978. Anal. Biochem. 91(1): 230-235. PMID: 9762103

6. Womack, M.D. et al. 1983. Biochim. Biophys. Acta. 733(2): 210-215. PMID: 6882760

7. Grohs, R.A. et al. 1991. Anal. Chem. 63(4): 384-390. PMID: 1823727

8. Gallagher, S.R. 2007. Curr Protoc Cell Biol. Chapter6 : Unit 6.1. PMID: 18228518

Appearance :

Crystalline

Physical State :

Solid

Solubility :

Soluble in water (150 g/L at 20° C), and ethanol (partly soluble).

保存方法 :

Store at room temperature

Melting Point :

204-207° C (lit.)

IC50 :

Human HepG2/C3A cells: IC₅₀ = 0.22 nM

Ki Data :

Displacement of C18-Aib-lucifer yellow from HIV1 envelope glycoprotein gp41 Fe(env2.0)3 receptor: K_i= 2000 nM

pK Values :

pK_a: -3.29 (Predicted)

試験・研究用以外には使用しないでください。臨床及び体外診断には使用できません。

WGK Germany :

RTECS :

WT1050000

PubChem CID :

3423265

Merck Index :

14: 8636

MDL Number :

MFCD00036175

EC Number :

205-788-1

Beilstein Registry :

3599286

SMILES :

CCCCCCCCCCCCOS(=O)(=O)[O-].[Na+]

Download SDS (MSDS)

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