RBP Antibody (20F9): sc-69795
- RBP Antibody (20F9) is a mouse monoclonal IgG1, cited in 5 publications, provided at 100 µl
- raised against purified RBP of human origin
- recommended for detection of RBP of mouse, rat and human origin by WB and IP
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for RBP Antibody (20F9). This work is in progress.
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RBP Antibody (20F9) is a mouse monoclonal IgG1 antibody that detects retinol-binding protein (RBP) in mouse, rat, and human samples through western blotting (WB) and immunoprecipitation (IP) applications. RBP plays a crucial role in the transport of retinol (Vitamin A) from the liver to peripheral tissues, which is essential for various physiological processes, including vision, immune function, and cellular growth. RBP is primarily located in the bloodstream, where RBP binds to retinol and interacts with transthyretin (TTR) to prevent filtration by the kidneys, thereby maintaining stability and functionality. The RBP-TTR complex is significant not only for retinol transport but also as a diagnostic marker for vitamin A deficiency, as the molar ratio of RBP to TTR can indicate marginal deficiencies. Furthermore, emerging research has linked elevated RBP levels in adipose tissue to insulin resistance, suggesting RBP may have a role in the pathogenesis of type 2 diabetes and obesity. Anti-RBP antibody (20F9) is an invaluable tool for researchers investigating the multifaceted roles of retinol-binding protein in health and disease.
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RBP Antibody (20F9) References:
- Retinol and retinol-binding protein: gut integrity and circulating immunoglobulins. | Quadro, L., et al. 2000. J Infect Dis. 182 Suppl 1: S97-S102. PMID: 10944490
- Metabolism of retinol-binding protein and vitamin A during hypervitaminosis A in the rat. | Mallia, AK., et al. 1975. J Lipid Res. 16: 180-8. PMID: 1127357
- Hepatic synthesis, maturation and complex formation between retinol-binding protein and transthyretin. | Gaetani, S., et al. 2002. Clin Chem Lab Med. 40: 1211-20. PMID: 12553421
- Retinol-binding protein is in the molten globule state at low pH. | Bychkova, VE., et al. 1992. Biochemistry. 31: 7566-71. PMID: 1510943
- The distribution of retinol-binding protein and its mRNA in the rat eye. | Herbert, J., et al. 1991. Invest Ophthalmol Vis Sci. 32: 302-9. PMID: 1993581
- Specific interaction of ivermectin with retinol-binding protein from filarial parasites. | Sani, BP. and Vaid, A. 1988. Biochem J. 249: 929-32. PMID: 3355505
- Radioimmunoassay of human plasma retinol-binding protein. | Smith, FR., et al. 1970. J Clin Invest. 49: 1754-61. PMID: 4988783
- Vitamin A and retinol-binding protein in amniotic fluid. | Wallingford, JC., et al. 1983. Am J Clin Nutr. 38: 377-81. PMID: 6684391
- Colchicine inhibition of retinol-binding protein secretion by rat liver. | Smith, JE., et al. 1980. J Lipid Res. 21: 229-37. PMID: 7189542
- The role of retinol-binding protein in protein-calorie malnutrition. | Ingenbleek, Y., et al. 1975. Metabolism. 24: 633-41. PMID: 805336
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
RBP Antibody (20F9) | sc-69795 | 100 µl | $322.00 |