(R)-BEL CAS: 478288-90-3
MF: C16H13BrO2
MW: 317.18
An iPLA2γ inhibitor.

(R)-BEL (CAS 478288-90-3)

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 151ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
別名: (R)-Bromoenol lactone
アプリケーション: (R)-BEL is an iPLA2γ inhibitor
CAS 番号: 478288-90-3
Purity: ≥98%
Molecular Weight: 317.18
Molecular Formula: C16H13BrO2
補足情報: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
試験・研究用以外には使用しないでください。 臨床及び体外診断には使用できません。
* Refer to Certificate of Analysis for lot specific data (including water content).

(R)-BEL is an irreversible, chiral, mechanism-based inhibitor of iPLA2γ (IC50 ~ 0.6 μM). Unlike (S)-BEL, (R)-BEL does not inhibit iPLA2β except at high doses (20-30 μM).


参考文献

1. Balsinde, J., et al., 1999. Regulation and inhibition of phospholipase A2. Annual review of pharmacology and toxicology. 39(): 175-89. PMID: 10331081
2. Jenkins, Christopher M., et al., 2002. Identification of calcium-independent phospholipase A2 (iPLA2) beta, and not iPLA2gamma, as the mediator of arginine vasopressin-induced arachidonic acid release in A-10 smooth muscle cells. Enantioselective mechanism-based discrimination of mammalian iPLA2s. The Journal of biological chemistry. 277(36): 32807-14. PMID: 12089145

Formulation :
Solution in methyl acetate
Physical State :
Liquid
保存方法 :
Store at -20° C
Boiling Point :
~467.0° C at 760 mmHg (Predicted)
試験・研究用以外には使用しないでください。 臨床及び体外診断には使用できません。
Transport :
UN 1231, Class 3, Packing group II
PubChem CID :
SMILES :
C12=CC=CC=C1C(=CC=C2)[[email protected]]3CCC(OC3=O)=CC

Download SDS (MSDS)

分析表

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 96ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 6ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

サンタクルーズバイオテクノロジーは生物医学研究市場向けの製品の開発における世界的リーダです。 下記フリー ダイヤルにお電話ください: 1-800-457-3801。Copyright © 2007-2021 Santa Cruz Biotechnology, Inc.全著作権所有。"Santa Cruz Biotechnology"、 及びSanta Cruz Biotechnology, Inc. ロゴ、 "Santa Cruz Animal Health"、 "San Juan Ranch"、 "Supplement of Champions"、 San Juan Ranch ロゴ、 "Ultracruz"、 "Chemcruz"、 "Immunocruz"、 "Exactacruz"、 と "EZ Touch"はサンタクルーズバイオテクノロジーの登録商標です。 商標はそれぞれの所有者に帰属します。