Polistes Mastoparan CAS: 74129-19-4
MF: C77H127N21O18
MW: 1634.96
A binder and inhibitor of calmodulin.

Polistes Mastoparan (CAS 74129-19-4)

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アプリケーション: A binder and inhibitor of calmodulin
CAS 番号: 74129-19-4
Molecular Weight: 1634.96
Molecular Formula: C77H127N21O18
* Refer to Certificate of Analysis for lot specific data (including water content).
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Polistes Mastoparan is a peptide found in wasp venom. It binds to and inhibits CAM (calmodulin), a calcium binding protein found in eukaryotic cells. It is suggested that a net positive charge on the peptide is important for anti-calmodulin activity because acetylation of the peptides is reported to reduce their inhibitory effect. It is also suggested that Polistes Mastoparan acts partly by stimulation of phospholipase activity.


参考文献

1. Nakajima, T., et al. 1985. Peptides. 6: 425-430. PMID: 3831970
2. Barnette, M.S., et al. 1983. Biochem. Pharmacol. 32: 2929-2933. PMID: 6313011
3. Argiolas, A., et al. 1983. J. Biol. Chem. 258: 13697-13702. PMID: 6643447

Physical State :
Solid
Solubility :
Soluble in Ethanol
保存方法 :
Store at -20° C
試験・研究用以外には使用しないでください。 臨床及び体外診断には使用できません。
WGK Germany :
3
PubChem CID :
16132143
SMILES :
CC[[email protected]](C)[[email protected]@H](C(=O)NCC(=O)N[[email protected]@H](CCC(=O)N)C(=O)N[[email protected]@H](CC1=CN=CN1)C(=O)N[[email protected]@H]([[email protected]@H](C)CC)C(=O)N[[email protected]@H](CC(C)C)C(=O)N[[email protected]@H](CO)C(=O)N[[email protected]@H](C(C)C)C(=O)N[[email protected]@H](CC(C)C)C(=O)N)NC(=O)[[email protected]](CCCCN)NC(=O)[[email protected]](CCCCN)NC(=O)[[email protected]](CC2=CNC3=CC=CC=C32)NC(=O)[[email protected]](CC(=O)O)NC(=O)[[email protected]](C(C)C)N

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