Phosphodiesterase V Inhibitor II
アプリケーション：
Phosphodiesterase V Inhibitor II is an inhibitor of phosphodiesterase
Purity:
≥97%
Molecular Weight:
403.5
Molecular Formula:
C24H25N3O3
試験・研究用以外には使用しないでください。 臨床及び体外診断には使用できません。
Phosphodiesterase V Inhibitor II is a cell-permeable tetrahydro-β-carboline-hydantoin compound. Acts as a potent and highly selective PDE (phosphodiesterase V inhibitor).
参考文献
Daugan, A., et al. 2003. J. Med. Chem. 46, 4533. Daugan, A., et al. 2003. J. Med. Chem. 46, 4525.
Physical State
:
Solid
Solubility
:
Soluble in DMSO (100 mg/ml), and ethanol.
保存方法
:
Store at 4° C
Melting Point
:
273.14° C (Predicted)
Boiling Point
:
584.75° C at 760 mmHg (Predicted)
Density
:
1.34 g/cm3 (Predicted)
Refractive Index
:
n20D 1.69 (Predicted)
IC50
:
PDE V: IC50 = 5 nM (bovine); Intracellular cGMP levels: EC5050 = 1 µM (ANF-treated RSMC); Recombinant PDE I & III: IC50 = > 10 µM (human); PDE II & IV: IC50 = > 10 µM (bovine)
試験・研究用以外には使用しないでください。 臨床及び体外診断には使用できません。
PubChem CID
:
MDL Number
:
MFCD09037550
SMILES
:
CCCCN1C(=O)C2CC3=C(C(N2C1=O)C4=CC=C(C=C4)OC)NC5=CC=CC=C35
Download SDS (MSDS)
分析表
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