Nitrocefin CAS: 41906-86-9
MF: C21H16N4O8S2
MW: 516.50

Nitrocefin (CAS 41906-86-9)

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別名: Nitrocefin is known as Nitrocephin.
アプリケーション: Nitrocefin is a chromogenic cephalosporin substrate, commonly used to detect β-lactamases in bacteria.
CAS 番号: 41906-86-9
Molecular Weight: 516.50
Molecular Formula: C21H16N4O8S2
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Nitrocefin is a chromogenic cephalosporin substrate, commonly used to detect β-lactamases in bacteria. This trait of Nitrocefin is highly desirable, as the generation of β-lactamases leads to resistance to several antibiotics including penicillins and cephalosporins. Nitrocefin indicates the presence of β-lactamase activity by the appearance of a red color. The red color produced by Nitrocefin is proportional in intensity to the original concentration of Nitrocefin.


参考文献

1. Worthington, R.J., and Melander, C.Overcoming resistance to β-lactam antibiotics. The Journal of Organic Chemistry 78(9), 4207-4213 (2013).
2. O′Callaghan, C.H., Morris, A., Kirby, S.M., et al.Novel method for detection of β-lactamases by using a chromogenic cephalosporin substrate. Antimicrobial Agents and Chemotherapy 1(4), 283-288 (1972).
3. Parr, T.R., Jr., Pai, C.H., and Bryan, L.E.Simple screening method for β-lactamase-positive and -negative ampicillin-resistant Haemophilus influenzae isolates. Journal of Clinical Microbiology 20(1), 131-132 (1984).
4. Coudron, P.E., Moland, E.S., and Sanders, C.C.Occurrence and detection of extended-spectrum β-lactamases in members of the family Enterobacteriaceae at a veterans medical center: Seek and you may find. Journal of Clinical Microbiology 35(10), 2593-2597 (1997).

Physical State :
Solid
保存方法 :
Store at -20° C
Melting Point :
>99° C (dec.)
試験・研究用以外には使用しないでください。 臨床及び体外診断には使用できません。

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