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MPP2 Antibody (A-7) is a mouse monoclonal IgM antibody that detects MPP2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). MPP2, also known as MAGUK p55 subfamily member 2 or discs large homolog 2, is a 576 amino acid protein that plays a crucial role in the organization of cell junctions and signaling pathways, which are essential for maintaining cellular integrity and communication. MPP2 belongs to the MAGUK (membrane-associated guanylate kinase homologs) family, characterized by multiple protein-binding domains, and exists in three alternatively spliced isoforms, each contributing to diverse functional roles. MPP2 contains a guanylate kinase-like domain, a PDZ (DHR) domain, two L27 domains, and a single SH3 domain, which facilitate interactions with various signaling molecules and structural proteins. The gene encoding MPP2 is located on human chromosome 17, in close proximity to MPP3, suggesting these proteins may share similar functions and structural characteristics, further emphasizing MPP2′s importance in cellular processes. Anti-MPP2 antibody (A-7) is an invaluable tool for researchers studying the dynamics of cell junctions and the signaling mechanisms that underpin various physiological and pathological conditions.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MPP2 Antibody (A-7) | sc-398939 | 200 µg/ml | $322.00 | |||
MPP2 (A-7) Neutralizing Peptide | sc-398939 P | 100 µg/0.5 ml | $69.00 |