KIF12 Antibody (A-9): sc-376766
- KIF12 Antibody (A-9) is a mouse monoclonal IgG2a κ, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 347-646 mapping at the C-terminus of KIF12 of human origin
- recommended for detection of KIF12 of human origin by WB, IP, IF, IHC(P) and ELISA
- m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for KIF12 Antibody (A-9) for WB and IHC(P) applications. These reagents are now offered in bundles with KIF12 Antibody (A-9) (see ordering information below).
KIF12 Antibody (A-9) is a mouse monoclonal IgG2a antibody that detects KIF12 in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). KIF12 is a kinesin-like protein composed of 651 amino acids, playing a crucial role in mitotically linked cytokinesis, which is essential for proper cell division. KIF12 is vital for the localization of myosin II during mitosis and is involved in the critical processes of nuclear separation during late anaphase and telophase. The structural features of KIF12, including its KISc domain, coiled-coil domain with an internal hinge region, and C-terminal tail domain, are significant as they facilitate motor activity and interaction with microtubules, ensuring accurate transport and positioning of cellular components. KIF12 mRNA expression is notably observed in various tissues, including fetal liver, adult brain, pancreatic islets, and is also implicated in certain cancers such as kidney tumors and pancreatic cancer, highlighting its potential as a biomarker for disease states. Anti-KIF12 antibody (A-9) is an invaluable tool for researchers studying the dynamics of cell division and the role of kinesins in cellular transport mechanisms.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
KIF12 Antibody (A-9) | sc-376766 | 200 µg/ml | $322.00 | |||
KIF12 Antibody (A-9): m-IgG Fc BP-HRP Bundle | sc-540641 | 200 µg Ab; 10 µg BP | $361.00 | |||
KIF12 Antibody (A-9): m-IgG2a BP-HRP Bundle | sc-546942 | 200 µg Ab; 10 µg BP | $361.00 |