hnRNP A1/HNRNPA1L2 Antibody (F-8): sc-365486
- hnRNP A1/HNRNPA1L2 Antibody (F-8) is a mouse monoclonal IgG1 κ, cited in 5 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 231-257 within an internal region of hnRNP A1 of human origin
- recommended for detection of hnRNP A1 and HNRNPA1L2 of mouse and human origin and hnRNP A1 of rat origin by WB, IP, IF, IHC(P) and ELISA
- See hnRNP A1 (4B10): sc-32301 for hnRNP A1/HNRNPA1L2 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for hnRNP A1/HNRNPA1L2 Antibody (F-8) for WB and IHC(P) applications. This reagent is now offered in a bundle with hnRNP A1/HNRNPA1L2 Antibody (F-8) (see ordering information below).
hnRNP A1/HNRNPA1L2 Antibody (F-8) is a mouse monoclonal IgG1 antibody that detects hnRNP A1 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). hnRNP A1 is a crucial member of the heterogeneous nuclear ribonucleoprotein (hnRNP) family, playing a significant role in mRNA transcription, pre-mRNA processing, and mature mRNA transport to the cytoplasm for translation. hnRNP A1 is primarily located in the nucleus, where binding to heterogeneous nuclear RNA (hnRNA) produced by RNA polymerase II occurs, proving essential for gene expression regulation. Anti-hnRNP A1 antibody (F-8) recognizes a protein that interacts with various splicing factors, influencing splice site selection and modulating pre-mRNA alternative splicing, which is vital for generating protein diversity and regulating cellular functions. hnRNP A1′s ability to shuttle between the nucleus and cytoplasm further underscores importance in post-transcriptional regulation, responding to cellular signals and participating in mRNA stability and transport. hnRNP A1 (F-8) antibody serves as an invaluable tool for researchers studying gene expression mechanisms and hnRNPs′ role in cellular processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
hnRNP A1/HNRNPA1L2 Antibody (F-8) | sc-365486 | 200 µg/ml | $322.00 | |||
hnRNP A1/HNRNPA1L2 Antibody (F-8): m-IgG Fc BP-HRP Bundle | sc-540344 | 200 µg Ab; 10 µg BP | $361.00 | |||
hnRNP A1 (F-8) Neutralizing Peptide | sc-365486 P | 100 µg/0.5 ml | $69.00 |