Molecular structure of GW 791343 hydrochloride, CAS Number: 309712-55-8
GW 791343 hydrochloride (CAS 309712-55-8)
Alternate Names:
2-[(3,4-Difluorophenyl)amino]-N-[2-methyl-5-(1-piperazinylmethyl)phenyl]-acetamide trihydrochloride
Application:
GW 791343 hydrochloride is a P2X7 allosteric modulator
CAS Number:
309712-55-8
Molecular Weight:
483.81
Molecular Formula:
C20H24F2N4O•3HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
P2X7 allosteric modulator. Exhibits species-specific activity and acts as a negative allosteric modulator of human P2X7 (pIC50 = 6.9 - 7.2). A positive allosteric modulator of rat P2X7.
GW 791343 hydrochloride (CAS 309712-55-8) References
Michel et al (2008) Negative and positive allosteric modulators of the P2X7 receptor. Br.J.Pharmacol. 153 737. Michel et al (2008) Identification of regions of the P2X7 receptor that contribute to human and rat species differences in antagonist effects. Br.J.Pharmacol. 155 738.Inhibitor of:
P2X7.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
GW 791343 hydrochloride, 10 mg | sc-203992 | 10 mg | $175.00 | |||
GW 791343 hydrochloride, 50 mg | sc-203992A | 50 mg | $739.00 |