GlcNAc1-β-3GalNAc (CAS 95673-98-6)

GlcNAc1-β-3GalNAc is a disaccharide involved in numerous research studies focusing on glycan structure and function. It consists of N-acetylglucosamine (GlcNAc) and N-acetylgalactosamine (GalNAc) linked through a β-1,3-glycosidic bond. This specific linkage is of considerable interest in the field of glycobiology as it mimics structural motifs found in mucin-type O-glycans, which play crucial roles in cell signaling and molecular recognition processes. The use of GlcNAc1-β-3GalNAc in research provides valuable insights into the biosynthesis and function of O-glycans, as well as their involvement in cellular communication pathways. Scientists utilize this disaccharide to study enzyme specificity and kinetics, particularly those of glycosyltransferases and glycosidases, which are enzymes that respectively add and remove sugar moieties from proteins and lipids. Moreover, it serves as a tool in probing the structural prerequisites for binding interactions with lectins, which are proteins that recognize specific carbohydrate structures. This chemical's role extends to the development of glycoconjugate materials for investigating cellular responses to external glycan presentations, thereby advancing the understanding of glycan-mediated biological processes. Through such applications, GlcNAc1-β-3GalNAc contributes significantly to fundamental research in carbohydrate chemistry and cell biology.