EBV Bam HI Z Antibody (5E265): sc-71021

EBV Bam HI Z Antibody (5E265) is a mouse monoclonal IgG2 antibody that detects the EBV Bam HI Z protein of Epstein-Barr Virus origin by western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Anti-EBV Bam HI Z antibody (5E265) is available as the non-conjugated format. EBV Bam HI Z protein plays a crucial role in the viral life cycle, particularly through association with the BZLF1 gene, which is essential for the transition from latent to lytic infection. This switch allows viral replication and spread, contributing to the pathogenesis of diseases such as infectious mononucleosis and various malignancies, including Burkitt lymphoma and nasopharyngeal carcinoma. Immediate early expression of EBV Bam HI Z protein is vital for initiating the lytic cycle, making EBV Bam HI Z (5E265) antibody a key tool for understanding EBV′s biology and impact on human health. Research using EBV Bam HI Z monoclonal antibody (5E265) can provide insights into the mechanisms of EBV infection and associated diseases, enhancing our understanding of this prevalent virus.

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EBV Bam HI Z Antibody (5E265) References:

1. Epstein-barr virus regulates c-MYC, apoptosis, and tumorigenicity in Burkitt lymphoma.  |  Ruf, IK., et al. 1999. Mol Cell Biol. 19: 1651-60. PMID: 10022853
2. Epstein-Barr Viral Antigens Used in the Diagnosis of Nasopharyngeal Carcinoma.  |  Gan, YY., et al. 1996. J Biomed Sci. 3: 159-169. PMID: 11725096
3. Characterization of T-cell non-Hodgkin's lymphoma and its association with Epstein-Barr virus in Pakistani patients.  |  Noorali, S., et al. 2003. Leuk Lymphoma. 44: 807-13. PMID: 12802918
4. Cell target genes of Epstein-Barr virus transcription factor EBNA-2: induction of the p55alpha regulatory subunit of PI3-kinase and its role in survival of EREB2.5 cells.  |  Spender, LC., et al. 2006. J Gen Virol. 87: 2859-2867. PMID: 16963743
5. Serodiagnosis of infectious mononucleosis by using recombinant Epstein-Barr virus antigens and enzyme-linked immunosorbent assay technology.  |  Gorgievski-Hrisoho, M., et al. 1990. J Clin Microbiol. 28: 2305-11. PMID: 2172287
6. Characterization of the restricted component of Epstein-Barr virus early antigens as a cytoplasmic filamentous protein.  |  Luka, J., et al. 1986. J Virol. 58: 748-56. PMID: 2422401
7. Neutralization of Epstein-Barr virus-induced ribonucleotide reductase with antibody to the major restricted early antigen polypeptide.  |  Goldschmidts, WL., et al. 1989. Virology. 170: 330-3. PMID: 2541553
8. [Studies on tissue distribution and expression of Epstein-Barr virus using polymerase chain reaction].  |  Oikawa, O. 1995. Hokkaido Igaku Zasshi. 70: 729-42. PMID: 8543279
9. Epstein-Barr virus BZLF1 gene, a switch from latency to lytic infection, is expressed as an immediate-early gene after primary infection of B lymphocytes.  |  Wen, W., et al. 2007. J Virol. 81: 1037-42. PMID: 17079287

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-EBV Bam HI Z Antibody (5E265) has 0 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

EBV Bam HI Z Antibody (5E265) Specifications

Alternate Product Name: EBV Bam HI Z

Product Clone Name: 5E265

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₂***

Amino Acids:

Epitope Target: EBV Bam HI Z

Epitope Species: EBV

Product Reactivity/Detection: Bam HI Z

Species Reactivity/Detection: Epstein-Barr Virus

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF

Vialing Information: Each vial contains 100 µg IgG₂*** in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for EBV Bam HI Z Antibody (5E265): N/A