DDX3 Antibody (6G8-F4-E3): sc-517564

DDX3 Antibody (6G8-F4-E3) is a mouse monoclonal IgG antibody that detects DDX3 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. DDX3, or DEAD box polypeptide 3, plays a crucial role in RNA metabolism and is essential for various cellular processes, including RNA splicing, transcription, translation initiation, mRNA transport, and cell cycle regulation. DDX3X, one of the two human paralogs of DDX3, is predominantly localized to nuclear speckles, which are important for the assembly and modification of RNA-protein complexes. This localization facilitates the efficient processing of pre-mRNA and the regulation of gene expression, impacting cellular growth and division. DDX3X is involved in the life cycle of certain viruses, including HIV-1 and hepatitis C, highlighting DDX3X′s importance in both normal cellular function and viral pathogenesis. Anti-DDX3 antibody (6G8-F4-E3) serves as an invaluable tool for researchers studying these critical processes and their implications in health and disease.