Cl-HIBO (CAS 909400-43-7)

身体の状態 :

Solid

溶解度 :

Soluble in water (20 mM), phosphate buffered saline (20 mM), and 1eq. NaOH (100 mM).

保存方法 :

Store at room temperature

融点 :

298.69° C (Predicted)

沸騰点 :

443.43° C (Predicted)

密度 :

~1.7 g/cm³ (Predicted)

屈折率 :

n²⁰_D 1.61 (Predicted)

IC50 :

Glutamate receptor ionotropic, AMPA 1: IC₅₀ = 0.22 µM (Rattus norvegicus); Glutamate receptor ionotropic, AMPA 2: EC₅₀50 = 1.7 µM (Rattus norvegicus); Glutamate receptor ionotropic, AMPA 2: EC₅₀50 = 1.7 µM (human); Glutamate receptor ionotropic, AMPA 1: EC₅₀50 = 4.1 µM (human); Glutamate receptor ionotropic, AMPA 1: EC₅₀50 = 4.7 µM (Mus musculus)

Ki データ :

Glutamate receptor ionotropic, AMPA 1: K_i= 130 nM (Rattus norvegicus); Glutamate receptor ionotropic, AMPA 2: K_i= 370 nM (human); Glutamate receptor ionotropic kainate 1: K_i= 6800 nM (human); Glutamate receptor ionotropic, AMPA 4: K_i= 11900 nM (Rattus norvegicus); Glutamate [NMDA] receptor subunit epsilon 3: K_i= 18000 nM (Rattus norvegicus)

輸送 :

Not available for sale outside of the United States.

PubChem CID :

SMILES :

C(C1=C(C(=O)NO1)Cl)C(C(=O)O)N