BNP Antibody (8D5B4C11): sc-101418
- BNP Antibody (8D5B4C11) is a mouse monoclonal IgG1, cited in 1 publications, provided at 200 µg/ml
- raised against a synthetic peptide corresponding to amino acids 112-124 of BNP of human origin
- recommended for detection of BNP of human origin by IF, IHC(P) and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for BNP Antibody (8D5B4C11). This work is in progress.
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BNP Antibody (8D5B4C11) is a mouse monoclonal IgG1 antibody that detects brain natriuretic peptide (BNP) in human samples through applications such as immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). BNP is a crucial cardiac hormone primarily produced by the ventricles in response to increased cardiac wall stress, playing a vital role in regulating blood pressure and fluid balance within the body. Anti-BNP antibody (8D5B4C11) promotes natriuresis and diuresis but also acts as a vasodilator, helping to alleviate the workload on the heart. BNP is characterized by a unique 17-residue ring structure stabilized by an intramolecular disulfide bond, which is essential for biological activity. The gene encoding BNP is located on human chromosome 1p36.22, and expression is tightly regulated, making BNP a valuable biomarker for heart failure and other cardiovascular conditions. BNP monoclonal antibody (8D5B4C11) is an indispensable tool for researchers studying cardiac function and the pathophysiology of heart diseases, providing insights into the mechanisms of fluid homeostasis and blood pressure regulation.
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BNP Antibody (8D5B4C11) References:
- Natriuretic peptides (BNP and NT-proBNP): measurement and relevance in heart failure. | Palazzuoli, A., et al. 2010. Vasc Health Risk Manag. 6: 411-8. PMID: 20539843
- The relationship among brain natriuretic peptide (BNP), cholesterol and lipoprotein. | Takeuchi, H. and Sata, M. 2012. Heart Asia. 4: 11-5. PMID: 27326018
- The prognostic value of brain natriuretic peptide (BNP) in non-cardiac patients with sepsis, ultra-long follow-up. | Khoury, J., et al. 2017. J Crit Care. 42: 117-122. PMID: 28719839
- Brain natriuretic peptide (BNP) expressing sensory neurons are not involved in acute, inflammatory or neuropathic pain. | Pitake, S., et al. 2017. Mol Pain. 13: 1744806917736993. PMID: 28969473
- Cutting Edge of Brain Natriuretic Peptide (BNP) Research - The Diversity of BNP Immunoreactivity and Its Clinical Relevance. | Kuwahara, K., et al. 2018. Circ J. 82: 2455-2461. PMID: 30135320
- BNP and NT-proBNP as Diagnostic Biomarkers for Cardiac Dysfunction in Both Clinical and Forensic Medicine. | Cao, Z., et al. 2019. Int J Mol Sci. 20: PMID: 31013779
- Brain Natriuretic Peptide (BNP) and N-Terminal-proBNP in Cardio-Renal Anemia Syndrome - Difference in Prognostic Ability. | Otaki, Y., et al. 2019. Circ Rep. 1: 71-77. PMID: 33693116
- Brain Natriuretic Peptide (BNP) Affects Growth and Stress Tolerance of Representatives of the Human Microbiome, Micrococcus luteus C01 and Alcaligenes faecalis DOS7. | Loiko, N., et al. 2022. Biology (Basel). 11: PMID: 36101364
- Inhibition of Fap Promotes Cardiac Repair by Stabilizing BNP. | Sun, Y., et al. 2023. Circ Res. 132: 586-600. PMID: 36756875
- BNP protects against diabetic cardiomyopathy by promoting Opa1-mediated mitochondrial fusion via activating the PKG-STAT3 pathway. | Chang, P., et al. 2023. Redox Biol. 62: 102702. PMID: 37116257
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
BNP Antibody (8D5B4C11) | sc-101418 | 200 µg/ml | $322.00 |