Bicyclomycin benzoate CAS: 37134-40-0
MF: C19H22N2O8
MW: 406.39

Bicyclomycin benzoate (CAS 37134-40-0)

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別名: Bicyclomycin benzoate is also known as Bicyclomycin, 3′-benzoate.
アプリケーション: Bicyclomycin benzoate is is a polar metabolite with activity against Gram negative bacteria including E. coli, Klebsiella, Shigella, Salmonella, Citroba
CAS 番号: 37134-40-0
Purity: ≥99%
Molecular Weight: 406.39
Molecular Formula: C19H22N2O8
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* Refer to Certificate of Analysis for lot specific data (including water content).

Bicyclomycin benzoate is a polar metabolite first isolated from Streptomyces sapporonensis in 1972 with activity against Gram negative bacteria. The selective Gram negative profile of Bicyclomycin benzoate is rare among Streptomyces metabolites, and in an effort to overcome its poor in vivo absorption, the benzoate ester was prepared by reaction with the more exposed primary alcohol.


参考文献

1. Bicyclomycin, a new antibiotic I. Taxonomy, isolation and characterization. Miyoshi T. et al. J. Antibiot. 1972, 25, 569. 2. Bicyclomycin, a new antibiotic II. Structural elucidation and acyl derivatives. Kamiya T. et al. J. Antibiot. 1972, 25, 576.

Physical State :
Solid
Solubility :
Soluble in ethanol, methanol, DMF, DMSO, and water (Partial).
保存方法 :
Store at -20° C
試験・研究用以外には使用しないでください。 臨床及び体外診断には使用できません。
RTECS :
DT7470000
PubChem CID :
71587135
SMILES :
C[[email protected]](COC(=O)C1=CC=CC=C1)([[email protected]@H](C23C(=O)N[[email protected]](C(=C)CCO2)(C(=O)N3)O)O)O

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Bicyclomycin benzoate (CAS 37134-40-0)  参考文献

See how others have used Bicyclomycin benzoate (CAS 37134-40-0). Click on the entry to view the PubMed entry .

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PMID: # 25661987  Pedrolli, D. et al. 2015. The FEBS journal. 282: 3230-42.

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