Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
G protein-coupled receptor kinases (GRKs) are activated by activated G protein-coupled receptors, and they function to phosphorylate and inactivate cell surface receptors in the heterotrimeric G protein signaling cascade. GIT1 (for GRK-interactor 1) and GIT2 are GTPase-activating proteins (GAPs) for members of the ADP ribosylation factor (ARF) family of small GTP-binding proteins, which are involved in vesicular trafficking. Another member of the ARF family, the cytoplasmic ARFGAP (ADP-ribosylation factor GTPase-activating protein) 1/3 protein, is involved in the dissociation of coat proteins from Golgi-derived membranes and vesicles. ARFGAP1/3, a cytoplasmic proten localizing to the perinuclear region, plays a role in protein secretion and vesicle transport and promotes hydrolysis of GTP bound to ARF-1. The activity of the ARFGAP1/3 protein is phospholipid sensitive. It is primarily expressed in endocrine glands and testis, but is also highly expressed in adult brain, thymus and lung.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.