AM 1172 (CAS 251908-92-6)

用法 :

To change the solvent, evaporate the ethanol under a gentle stream of nitrogen and immediately add the solvent of choice.

処方 :

Solution in ethanol

身体の状態 :

Liquid

溶解度 :

Soluble in water (0.15 mg/ml at 20° C), ethanol, DMSO (~30 mg/ml), DMF (~30 mg/ml), and PBS pH 7.2 (~0.15 mg/ml).

保存方法 :

Store at -20° C

沸騰点 :

78° C

屈折率 :

n²⁰_D 1.54 (Predicted)

IC50 :

CB2: EC₅₀50 = 189 nM; Uptake of tritiated AEA: EC₅₀50 = 1.5 µM; Anandamide uptake: IC₅₀ = 2.1-2.5 µM; N-arachidonylethanolamine accumulation: IC₅₀ = 24 µM; N-palmitoylethanolamine hydrolysis: IC₅₀ = 36 µM

Ki データ :

N-arachidonylethanolamine hydrolysis: K_i= 3 µM; FAAH: K_i= 3.18 µM

RTECS :

CV4830000

PubChem CID :

MDL番号 :

MFCD08062148

SMILES :

CCCCC/C=C\\C/C=C\\C/C=C\\C/C=C\\CCCCNC(=O)C1=CC=C(C=C1)O