
UROD Antibody (G-7) is a mouse monoclonal IgG1 antibody that detects uroporphyrinogen decarboxylase (UROD) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). UROD is a crucial enzyme in the heme biosynthetic pathway, functioning as the fifth enzyme responsible for converting uroporphyrinogen to coproporphyrinogen by removing four carboxymethyl side chains. This enzymatic activity is vital for maintaining proper heme levels in the body, as heme is essential for various biological processes, including oxygen transport and electron transfer in cellular respiration. Disruptions in UROD function due to mutations in the UROD gene can lead to serious autosomal disorders such as familial porphyria cutanea tarda, sporadic porphyria cutanea tarda, and hepatoerythropoietic porphyria, each associated with significant clinical manifestations. Anti-UROD antibody (G-7) provides a reliable tool for researchers studying these conditions, allowing for the exploration of UROD′s role in disease mechanisms and potential therapeutic interventions.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
UROD Antibody (G-7) | sc-374318 | 200 µg/ml | $322.00 | |||
UROD Antibody (G-7): m-IgG Fc BP-HRP Bundle | sc-540434 | 200 µg Ab; 10 µg BP | $361.00 | |||
UROD Antibody (G-7): m-IgG1 BP-HRP Bundle | sc-542120 | 200 µg Ab; 20 µg BP | $361.00 |