Pol II RPB5 Antibody (3Y11) is a mouse monoclonal IgG1 antibody that detects Pol II RPB5 protein of yeast origin by western blotting (WB). Anti-Pol II RPB5 antibody (3Y11) is available in a non-conjugated form, specifically designed for researchers seeking to study the role of this essential protein in transcription. The POLR2E gene encodes RPB5 protein, which is a critical component of RNA polymerase II, responsible for synthesizing messenger RNA from DNA templates. RPB5 protein is located in the nucleus, where RPB5 plays a pivotal role in the transcription process, facilitating the assembly of the RNA polymerase complex and ensuring accurate gene expression. Proper functioning of RPB5 is vital, as RPB5 not only influences the transcription of protein-coding genes but also impacts various cellular processes, including cell growth and differentiation. Understanding the dynamics of RPB5 and interactions with other transcription factors can provide insights into the regulation of gene expression and the underlying mechanisms of various diseases.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Pol II RPB5 Antibody (3Y11) References:
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