Molecular structure of Methylstat, CAS Number: 1310877-95-2
Methylstat (CAS 1310877-95-2)
Alternate Names:
methyl (E)-4-[hydroxy-[4-[[4-(naphthalen-1-ylcarbamoyloxymethyl)phenyl]methylamino]butyl]amino]-4-oxobut-2-enoate
CAS Number:
1310877-95-2
Molecular Weight:
505.56
Molecular Formula:
C28H31N3O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Methylstat (CAS 1310877-95-2) References
- A selective inhibitor and probe of the cellular functions of Jumonji C domain-containing histone demethylases. | Luo, X., et al. 2011. J Am Chem Soc. 133: 9451-6. PMID: 21585201
- Quantitative analysis of histone demethylase probes using fluorescence polarization. | Xu, W., et al. 2013. J Med Chem. 56: 5198-202. PMID: 23725560
- Regulatory link between DNA methylation and active demethylation in Arabidopsis. | Lei, M., et al. 2015. Proc Natl Acad Sci U S A. 112: 3553-7. PMID: 25733903
- A model for the aberrant DNA methylomes in aging cells and cancer cells. | Zhang, H., et al. 2019. Biochem Soc Trans. 47: 997-1003. PMID: 31320500
- Therapeutic Potentials of Inhibition of Jumonji C Domain-containing Demethylases in Acute Myeloid Leukemia. | Koca, D., et al. 2020. Turk J Haematol. 37: 5-12. PMID: 31833715
- Synergistic Apoptotic Effects of Bortezomib and Methylstat on Multiple Myeloma Cells. | Kacı, FN., et al. 2020. Arch Med Res. 51: 187-193. PMID: 32111493
- Identification of potential repurposed drugs for treating endometriosis-associated infertility among women. | Nayak, R., et al. 2022. Chem Biol Interact. 365: 110110. PMID: 35985520
- Loss of SUV420H2-Dependent Chromatin Compaction Drives Right-Sided Colon Cancer Progression. | Boonsanay, V., et al. 2023. Gastroenterology. 164: 214-227. PMID: 36402192
- Epidrugs: alternative chemotherapy targeting Theileria annulata schizont stage parasites. | Kamble, S., et al. 2024. Microbiol Spectr. 12: e0325823. PMID: 38421193
- Cytoskeletal rearrangement precedes nucleolar remodeling during adipogenesis. | Potolitsyna, E., et al. 2024. Commun Biol. 7: 458. PMID: 38622242
Inhibitor of:
ALKBH3, ALKBH4, Blimp-1, JMJD1B, JMJD2B, JMJD2C, JMJD4, JMJD8, TET2, UTY, and VPS37D.Activator of:
BRWD3, E(z), EMID2, FAM208A, H2BFWT, Histone cluster 1 H2AF, Histone cluster 1 H2BL, Histone cluster 1 H4H, Histone H10, Histone H2A.F, Histone H2BM, HKDC1, kismet, L3MBTL, LSD1, MBD2, periphilin 1, PHF20L1, RNF20, SETD6, SFMBT1, STH1, SUV39H1, UHRF1, and WIZ.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Methylstat, 10 mg | sc-507374 | 10 mg | $480.00 |