KIF12 Antibody (H-5): sc-376980
- KIF12 Antibody (H-5) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against amino acids 352-642 mapping at the C-terminus of KIF12 of mouse origin
- recommended for detection of KIF12 of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for KIF12 Antibody (H-5) for WB applications. These reagents are now offered in bundles with KIF12 Antibody (H-5) (see ordering information below).
KIF12 Antibody (H-5) is a mouse monoclonal IgG1 antibody that detects KIF12 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). KIF12 is a kinesin-like protein consisting of 651 amino acids, playing a crucial role in mitotically linked cytokinesis, which is essential for proper cell division. KIF12 (H-5) antibody helps researchers study protein localization of myosin II during mitosis and involvement in nuclear separation during late anaphase and telophase. The structure of KIF12 includes a KISc domain, a coiled-coil domain with an internal hinge region, and a C-terminal tail domain, which are important for motor activity and interaction with microtubules. The precise arrangement of these structural elements allows KIF12 to effectively transport cellular components, ensuring essential molecules are accurately delivered to their destinations within the cell. KIF12 mRNA is expressed in various tissues, including fetal liver, adult brain, pancreatic islets, and is notably present in kidney tumors as well as uterine and pancreatic cancers, highlighting potential significance in both normal physiology and disease states. Anti-KIF12 antibody (H-5) serves as an invaluable tool for researchers studying the dynamics of cell division and the role of kinesins in cellular transport mechanisms.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
KIF12 Antibody (H-5) | sc-376980 | 200 µg/ml | $322.00 | |||
KIF12 Antibody (H-5): m-IgG Fc BP-HRP Bundle | sc-540679 | 200 µg Ab; 10 µg BP | $361.00 | |||
KIF12 Antibody (H-5): m-IgG1 BP-HRP Bundle | sc-542294 | 200 µg Ab; 20 µg BP | $361.00 |