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Imidapril hydrochloride (CAS 89371-37-9)

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Alternate Names:
Imidapril monohydrochloride
Application:
Imidapril hydrochloride is an inhibitor of ACE (angiotension converting enzyme)
CAS Number:
89371-37-9
Molecular Weight:
441.91
Molecular Formula:
C20H27N3O6•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

An inhibitor of angiotensin converting enzyme (ACE). Antihypertensive.


Imidapril hydrochloride (CAS 89371-37-9) References

  1. Protection of the cardiovascular system by imidapril, a versatile angiotensin-converting enzyme inhibitor.  |  Hosoya, K. and Ishimitsu, T. 2002. Cardiovasc Drug Rev. 20: 93-110. PMID: 12177688
  2. LC-MS determination and bioavailability study of imidapril hydrochloride after the oral administration of imidapril tablets in human volunteers.  |  Yun, JH., et al. 2005. Arch Pharm Res. 28: 463-8. PMID: 15918521
  3. Imidapril in heart failure.  |  Dolezal, T. 2006. J Renin Angiotensin Aldosterone Syst. 7: 146-54. PMID: 17094051
  4. UV derivative spectrophotometric and RP-HPLC methods for determination of imidapril hydrochloride in tablets and for its stability assessment in solid state.  |  Stanisz, B., et al. 2011. Acta Pol Pharm. 68: 645-51. PMID: 21928708
  5. Imidapril inhibits cerebral aneurysm formation in an angiotensin-converting enzyme-independent and matrix metalloproteinase-9-dependent manner.  |  Ishibashi, R., et al. 2012. Neurosurgery. 70: 722-30. PMID: 21937941
  6. Imidapril inhibits right ventricular remodeling induced by low ambient temperature in broiler chickens.  |  Hao, XQ., et al. 2013. Poult Sci. 92: 1492-7. PMID: 23687144
  7. Optimization of storage and manufacture conditions for imidapril hydrochloride in solid state as a way to reduce costs of antihypertensive therapy.  |  Regulska, K., et al. 2013. AAPS PharmSciTech. 14: 1199-208. PMID: 23907513
  8. Kinetics of degradation of imidapril hydrochloride in finished dosage formulations.  |  Stanisz, B. and Regulska, K. 2013. Acta Pol Pharm. 70: 737-42. PMID: 23923397
  9. Rosiglitazone and imidapril alone or in combination alleviate muscle and adipose depletion in a murine cancer cachexia model.  |  Chen, SZ. and Xiao, JD. 2014. Tumour Biol. 35: 323-32. PMID: 23959470
  10. Is there any association between imidapril hydrochloride stability profile under dry air conditions and cancer initiation?  |  Regulska, K., et al. 2013. Int J Pharm. 456: 332-9. PMID: 24021249
  11. The mutagenicity analysis of imidapril hydrochloride and its degradant, diketopiperazine derivative, nitrosation mixtures by in vitro Ames test with two strains of Salmonella typhimurium.  |  Regulska, K., et al. 2014. Rep Pract Oncol Radiother. 19: 412-9. PMID: 25337415
  12. Systemic, regional and cerebral hemodynamic effects of a new angiotensin converting enzyme inhibitor, imidapril, in healthy volunteers.  |  Démolis, P., et al. 1994. Fundam Clin Pharmacol. 8: 80-9. PMID: 8181800
  13. Dose finding studies with imidapril--a new ACE inhibitor.  |  Vandenburg, MJ., et al. 1994. Br J Clin Pharmacol. 37: 265-72. PMID: 8198936

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Imidapril hydrochloride, 10 mg

sc-207751
10 mg
$105.00