Cytokeratin 10 Antibody (AE20): sc-80608
- Cytokeratin 10 Antibody (AE20) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- raised against Cytokeratin 10 of human origin
- recommended for detection of Cytokeratin 10 of mouse, rat and human origin by WB, IP, IF and IHC(P)
- See Cytokeratin 10 (LH2): sc-53252 for Cytokeratin 10 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Cytokeratin 10 Antibody (AE20) for WB and IHC(P) applications. These reagents are now offered in bundles with Cytokeratin 10 Antibody (AE20) (see ordering information below).
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Cytokeratin 10 Antibody (AE20) is a mouse monoclonal IgG1 antibody that detects Cytokeratin 10 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. Anti-Cytokeratin 10 antibody (AE20) forms a heterotetramer with keratin 1, contributing to the structural integrity and resilience of epithelial cells. Cytokeratin 10 monoclonal antibody (AE20) targets proteins predominantly located in the suprabasal layers of the epidermis, including the stratum corneum, where Cytokeratin 10 plays a vital role in maintaining the barrier function of the skin. Cytokeratin 10 (AE20) antibody helps identify expression patterns that serve as markers for various skin conditions and malignancies, including squamous cell carcinomas. Anti-Cytokeratin 10 antibody (AE20) enables researchers to gain insights into the differentiation status of epithelial tissues and the underlying mechanisms of tumorigenesis, making this tool valuable for both basic research and clinical applications.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Cytokeratin 10 Antibody (AE20) References:
- Cytokeratin 10/13, 14, 7, 8, and 18 in invasive squamous cell carcinoma and adenocarcinoma of the uterine cervix. | Heatley, MK. 1999. J Clin Pathol. 52: 789. PMID: 10674044
- Differentiation of odontogenic keratocysts from nonkeratinizing cysts by use of fine-needle aspiration biopsy and cytokeratin-10 staining. | August, M., et al. 2000. J Oral Maxillofac Surg. 58: 935-40; discussion 940-1. PMID: 10981972
- Cytokeratin 10 and Ki-67 nuclear marker expression in keratoacanthoma and squamous cell carcinoma. | Basta-Juzbasić, A., et al. 2004. Acta Dermatovenerol Croat. 12: 251-6. PMID: 15588557
- Cytokeratin 10 and cytokeratin 19: predictive markers for poor prognosis in hepatocellular carcinoma patients after curative resection. | Yang, XR., et al. 2008. Clin Cancer Res. 14: 3850-9. PMID: 18559605
- Cytokeratin 10-negative nested pattern enables sure distinction of clonal seborrheic keratosis from pagetoid Bowen's disease. | Böer-Auer, A., et al. 2012. J Cutan Pathol. 39: 225-33. PMID: 22236073
- Loss of cytokeratin 10 indicates malignant transformation in actinic cheilitis. | Garcia, NG., et al. 2016. Clin Oral Investig. 20: 745-52. PMID: 26264639
- Increase of cystathionine-γ-lyase (CSE) during late wound repair: Hydrogen sulfide triggers cytokeratin 10 expression in keratinocytes. | Goren, I., et al. 2019. Nitric Oxide. 87: 31-42. PMID: 30862476
- Kallikrein-Mediated Cytokeratin 10 Degradation Is Required for Varicella Zoster Virus Propagation in Skin. | Tommasi, C., et al. 2020. J Invest Dermatol. 140: 774-784.e11. PMID: 31626786
- Allantodapsone is a Pan-Inhibitor of Staphylococcus aureus Adhesion to Fibrinogen, Loricrin, and Cytokeratin 10. | Prencipe, F., et al. 2022. Microbiol Spectr. 10: e0117521. PMID: 35647689
- Gene targeting at the mouse cytokeratin 10 locus: severe skin fragility and changes of cytokeratin expression in the epidermis. | Porter, RM., et al. 1996. J Cell Biol. 132: 925-36. PMID: 8603923
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cytokeratin 10 Antibody (AE20) | sc-80608 | 200 µg/ml | $322.00 | |||
Cytokeratin 10 Antibody (AE20): m-IgG Fc BP-HRP Bundle | sc-539568 | 200 µg Ab; 10 µg BP | $361.00 | |||
Cytokeratin 10 Antibody (AE20): m-IgG1 BP-HRP Bundle | sc-541563 | 200 µg Ab; 20 µg BP | $361.00 |