alpha-dystroglycan Antibody D-3 è un monoclonale di topo IgG2a κ, citato in 1 pubblicazioni, fornito in 200 µg/ml
generato contro gli amminoacidi 30-329 mappati vicino al N-terminus di dystroglycan precursor di origine human
alpha-dystroglycan Antibody (D-3) é raccomandato per il rilevamento di α-dystroglycan di origine mouse, rat e human in WB, IP, IF e ELISA
alpha-dystroglycan Antibody (D-3) é disponibile coniugato con agarose per IP; HRP per WB, IHC(P) ed ELISA; sia con phycoerythrin o FITC per IF, IHC(P) e FCM
disponibile anche coniugato con Alexa Fluor® 488, Alexa Fluor® 546; Alexa Fluor® 594 o Alexa Fluor® 647 per IF, IHC (P) e FCM
disponibile anche coniugato con Alexa Fluor® 680 o Alexa Fluor® 790 per WB (NIR), IF e FCM
Contattaci per ricevere un FREE 10 µg sample di α-dystroglycan (D-3): sc-271589.
m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for α-dystroglycan Antibody (D-3) for WB applications. These reagents are now offered in bundles with α-dystroglycan Antibody (D-3) (see ordering information below).
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Dystroglycan (DG) is a cell surface receptor for several extracellular matrix molecules including laminins, Agrin and Perlecan. Dystroglycan function is required for the formation of basement membranes in early development and the organization of Laminin on the cell surface. α-dystroglycan is a membrane- associated, extracellular glycoprotein that is anchored to the cell-membrane by binding to the transmembrane glycoprotein α-dystroglycan to form an α/β-dystroglycan-complex. Additionally, dystroglycan is part of a multimolecular complex, where it associates with dystrophin, at the sarcolemma, to form the dystrophin-associated protein complex, or with utrophin, at the neuromuscular junction, to form the utrophin-associated protein complex. Dystroglycan is also thought to participate in the clustering of nicotinic acetylcholine receptors at the neuromuscular junction.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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