AdoMetDC Antibody (F-10): sc-398482
- AdoMetDC Antibody (F-10) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 211-224 within an internal region of AdoMetDC of human origin
- recommended for detection of AdoMetDC of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, bovine and porcine
- m-IgG Fc BP-HRP, m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for AdoMetDC Antibody (F-10) for WB applications. These reagents are now offered in bundles with AdoMetDC Antibody (F-10) (see ordering information below).
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SEE ALSO...
AdoMetDC Antibody (F-10) is a mouse monoclonal IgG2b antibody that detects AdoMetDC in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). AdoMetDC, or adenylmethionine decarboxylase 1, is a crucial enzyme in the polyamine biosynthesis pathway, consisting of 334 amino acids. AdoMetDC monoclonal antibody (F-10) plays a vital role in studying cellular growth and proliferation, making AdoMetDC significant in various biological processes, including tumor promotion. AdoMetDC is synthesized as an inactive proenzyme that undergoes self-maturation to produce two distinct subunits, α and β, which then assemble into an active heterotetramer composed of two α chains and two β chains. The enzymatic activity of AdoMetDC is essential for the conversion of S-adenosyl-L-methionine into biologically active polyamines, which are necessary for cell division and differentiation. Notably, the processing of the AdoMetDC proenzyme and its catalytic activity are enhanced by putrescine, while iodoacetic acid serves as an inhibitor, highlighting the regulatory mechanisms that control polyamine synthesis. Anti-AdoMetDC antibody (F-10) serves as an invaluable tool for researchers studying the dynamics of polyamine metabolism and its implications in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
AdoMetDC Antibody (F-10) | sc-398482 | 200 µg/ml | $322.00 | |||
AdoMetDC Antibody (F-10): m-IgG Fc BP-HRP Bundle | sc-538452 | 200 µg Ab; 10 µg BP | $361.00 | |||
AdoMetDC Antibody (F-10): m-IgGκ BP-HRP Bundle | sc-536071 | 200 µg Ab; 40 µg BP | $361.00 | |||
AdoMetDC Antibody (F-10): m-IgG2b BP-HRP Bundle | sc-549950 | 200 µg Ab; 10 µg BP | $361.00 | |||
AdoMetDC (F-10) Neutralizing Peptide | sc-398482 P | 100 µg/0.5 ml | $69.00 |