5β-Cholanic acid-3α, 6α, 7β-triol (CAS 6830-03-1)
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Alternate Names:
ω-Muricholic acid
Application:
5β-Cholanic acid-3α, 6α, 7β-triol is a cholesterol used for proteomics research
CAS Number:
6830-03-1
Molecular Weight:
408.57
Molecular Formula:
C24H40O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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5beta-Cholanic acid-3alpha, 6alpha, 7beta-triol is a cholesterol used for proteomics research. A member of the class of muricholic acids in which the hydroxy groups at positions 6 and 7 have alpha and beta configuration, respectively. A murine-specific secondary bile acid. It is formed via enzymatic conversion of β-MCA by a variety of intestinal microorganisms, including Clostridium, in rat and mouse gut.
5β-Cholanic acid-3α, 6α, 7β-triol (CAS 6830-03-1) References
- Improved analysis of bile acids in tissues and intestinal contents of rats using LC/ESI-MS. | Hagio, M., et al. 2009. J Lipid Res. 50: 173-80. PMID: 18772484
- Regulation of bile acid synthesis by fat-soluble vitamins A and D. | Schmidt, DR., et al. 2010. J Biol Chem. 285: 14486-94. PMID: 20233723
- Voluntary wheel running exercise and dietary lactose concomitantly reduce proportion of secondary bile acids in rat feces. | Hagio, M., et al. 2010. J Appl Physiol (1985). 109: 663-8. PMID: 20616226
- Bile acid analysis in various biological samples using ultra performance liquid chromatography/electrospray ionization-mass spectrometry (UPLC/ESI-MS). | Hagio, M., et al. 2011. Methods Mol Biol. 708: 119-29. PMID: 21207286
- Targeted profiling of circulating and hepatic bile acids in human, mouse, and rat using a UPLC-MRM-MS-validated method. | García-Cañaveras, JC., et al. 2012. J Lipid Res. 53: 2231-2241. PMID: 22822028
- Simultaneous and rapid analysis of bile acids including conjugates by supercritical fluid chromatography coupled to tandem mass spectrometry. | Taguchi, K., et al. 2013. J Chromatogr A. 1299: 103-9. PMID: 23768533
- High-fat Diet-induced Intestinal Hyperpermeability is Associated with Increased Bile Acids in the Large Intestine of Mice. | Murakami, Y., et al. 2016. J Food Sci. 81: H216-22. PMID: 26595891
- Combination of soya pulp and Bacillus coagulans lilac-01 improves intestinal bile acid metabolism without impairing the effects of prebiotics in rats fed a cholic acid-supplemented diet. | Lee, Y., et al. 2016. Br J Nutr. 116: 603-10. PMID: 27464459
- Ingestion of difructose anhydride III partially suppresses the deconjugation and 7α-dehydroxylation of bile acids in rats fed with a cholic acid-supplemented diet. | Lee, DG., et al. 2019. Biosci Biotechnol Biochem. 83: 1329-1335. PMID: 30912732
- Association between 12α-hydroxylated bile acids and hepatic steatosis in rats fed a high-fat diet. | Hori, S., et al. 2020. J Nutr Biochem. 83: 108412. PMID: 32534424
- 12α-Hydroxylated bile acid induces hepatic steatosis with dysbiosis in rats. | Lee, JY., et al. 2020. Biochim Biophys Acta Mol Cell Biol Lipids. 1865: 158811. PMID: 32896622
- Primary 12α-Hydroxylated Bile Acids Lower Hepatic Iron Concentration in Rats. | Hori, S., et al. 2021. J Nutr. 151: 523-530. PMID: 33438034
- Dietary raffinose ameliorates hepatic lipid accumulation induced by cholic acid via modulation of enterohepatic bile acid circulation in rats. | Maegawa, K., et al. 2022. Br J Nutr. 127: 1621-1630. PMID: 34256877
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
5β-Cholanic acid-3α, 6α, 7β-triol, 1 mg | sc-396738 | 1 mg | $362.00 |