Date published: 2026-7-21

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TREK Antibodies

Santa Cruz Biotechnology features a diverse variety of TREK Antibodies for advanced research in ion channel biology. TREK Antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). TREK proteins, part of the two-pore domain potassium channel family, play a crucial role in regulating cellular excitability and maintaining the resting membrane potential. TREK channels are actively involved in neuronal signaling, cardiac function, and response to mechanical stress. Research focusing on TREK proteins continues to reveal significant insights into health and disease, particularly in conditions such as pain, ischemia, and neurodegenerative disorders. Scientists worldwide utilize TREK monoclonal antibodies to advance their understanding of ion channel dynamics and cellular signaling pathways. Ongoing studies of TREK channels have highlighted their importance in maintaining cellular homeostasis and their potential as therapeutic targets. TREK monoclonal antibodies from Santa Cruz Biotechnology enable researchers to make meaningful contributions to the scientific understanding of ion channel biology and its impact on human health.

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TREK Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

TREK-1 Antibody (F-6)

sc-398449mouse IgM κ354-380 (h)WB, IP, IF, ELISAm, r, h
11
(5)

TREK-2 Antibody (1C1)

sc-293332mouse IgG1 κ439-538 (h)WB, IP, ELISAh
1
(1)

TREK siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

TREK-1 siRNA (h)

sc-37180hGene SilencingN/A
1
(0)

TREK-1 shRNA Plasmid (h)

sc-37180-SHhGene SilencingPuromycin
1
(0)

TREK-1 shRNA (h) Lentiviral Particles

sc-37180-VhGene SilencingPuromycin
1
(0)

TREK-1 siRNA (m)

sc-37181mGene SilencingN/A
1
(0)

TREK-1 shRNA Plasmid (m)

sc-37181-SHmGene SilencingPuromycin
1
(0)

TREK-1 shRNA (m) Lentiviral Particles

sc-37181-VmGene SilencingPuromycin
1
(0)

TREK-1 siRNA (r)

sc-270403rGene SilencingN/A0
(0)

TREK-1 shRNA Plasmid (r)

sc-270403-SHrGene SilencingPuromycin0
(0)

TREK-1 shRNA (r) Lentiviral Particles

sc-270403-VrGene SilencingPuromycin0
(0)

TREK-2 siRNA (h)

sc-42347hGene SilencingN/A
1
(0)

TREK-2 shRNA Plasmid (h)

sc-42347-SHhGene SilencingPuromycin
1
(0)

TREK-2 shRNA (h) Lentiviral Particles

sc-42347-VhGene SilencingPuromycin
1
(0)

TREK-2 siRNA (m)

sc-42348mGene SilencingN/A0
(0)

TREK-2 shRNA Plasmid (m)

sc-42348-SHmGene SilencingPuromycin0
(0)

TREK-2 shRNA (m) Lentiviral Particles

sc-42348-VmGene SilencingPuromycin0
(0)

TREK CRISPR Knockout (KO) and HDR Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

TREK-1 CRISPR/Cas9 KO Plasmid (h2)

sc-402212-KO-2Gene Knockouth0
(0)

TREK-1 HDR Plasmid (h2)

sc-402212-HDR-2Homology Directed Repairh0
(0)

TREK-1 CRISPR/Cas9 KO Plasmid (m)

sc-421244Gene Knockoutm0
(0)

TREK-1 HDR Plasmid (m)

sc-421244-HDRHomology Directed Repairm0
(0)

TREK CRISPR Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

TREK-1 Double Nickase Plasmid (h)

sc-402212-NICGene Knockouth0
(0)

TREK-1 Double Nickase Plasmid (h2)

sc-402212-NIC-2Gene Knockouth0
(0)

TREK CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

TREK-1 CRISPR Activation Plasmid (m)

sc-421244-ACTGene Activationm0
(0)

TREK-1 CRISPR Activation Plasmid (m2)

sc-421244-ACT-2Gene Activationm0
(0)

TREK-1 Lentiviral Activation Particles (m)

sc-421244-LACGene Activationm0
(0)