Date published: 2026-6-4

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TREK Antibodies

Santa Cruz Biotechnology features a diverse variety of TREK Antibodies for advanced research in ion channel biology. TREK Antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). TREK proteins, part of the two-pore domain potassium channel family, play a crucial role in regulating cellular excitability and maintaining the resting membrane potential. TREK channels are actively involved in neuronal signaling, cardiac function, and response to mechanical stress. Research focusing on TREK proteins continues to reveal significant insights into health and disease, particularly in conditions such as pain, ischemia, and neurodegenerative disorders. Scientists worldwide utilize TREK monoclonal antibodies to advance their understanding of ion channel dynamics and cellular signaling pathways. Ongoing studies of TREK channels have highlighted their importance in maintaining cellular homeostasis and their potential as therapeutic targets. TREK monoclonal antibodies from Santa Cruz Biotechnology enable researchers to make meaningful contributions to the scientific understanding of ion channel biology and its impact on human health.

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TREK Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

TREK-1 Antibody (F-6)

sc-398449mouse IgM κ354-380 (h)WB, IP, IF, ELISAm, r, h
11
(5)

TREK-2 Antibody (1C1)

sc-293332mouse IgG1 κ439-538 (h)WB, IP, ELISAh
1
(1)

TREK CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

TREK-1 CRISPR/Cas9 KO Plasmid (h2)

sc-402212-KO-2hGene KnockoutGFP0
(0)

TREK-1 HDR Plasmid (h2)

sc-402212-HDR-2hHomology Directed RepairPuromycin0
(0)

TREK-1 Double Nickase Plasmid (h)

sc-402212-NIChGene KnockoutPuromycin0
(0)

TREK-1 Double Nickase Plasmid (h2)

sc-402212-NIC-2hGene KnockoutPuromycin0
(0)

TREK-1 CRISPR/Cas9 KO Plasmid (m)

sc-421244mGene KnockoutGFP
1
(0)

TREK-1 HDR Plasmid (m)

sc-421244-HDRmHomology Directed RepairPuromycin
1
(0)

TREK CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

TREK-1 CRISPR Activation Plasmid (m)

sc-421244-ACTmGene ActivationPuro, Blast, Hygro
1
(0)

TREK-1 CRISPR Activation Plasmid (m2)

sc-421244-ACT-2mGene ActivationPuro, Blast, Hygro
1
(0)

TREK-1 Lentiviral Activation Particles (m)

sc-421244-LACmGene ActivationPuro, Blast, Hygro
1
(0)

TREK siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

TREK-1 siRNA (h)

sc-37180hGene SilencingN/A
1
(0)

TREK-1 shRNA Plasmid (h)

sc-37180-SHhGene SilencingPuromycin
1
(0)

TREK-1 shRNA (h) Lentiviral Particles

sc-37180-VhGene SilencingPuromycin
1
(0)

TREK-1 siRNA (m)

sc-37181mGene SilencingN/A
1
(0)

TREK-1 shRNA Plasmid (m)

sc-37181-SHmGene SilencingPuromycin
1
(0)

TREK-1 shRNA (m) Lentiviral Particles

sc-37181-VmGene SilencingPuromycin
1
(0)

TREK-1 siRNA (r)

sc-270403rGene SilencingN/A0
(0)

TREK-1 shRNA Plasmid (r)

sc-270403-SHrGene SilencingPuromycin0
(0)

TREK-1 shRNA (r) Lentiviral Particles

sc-270403-VrGene SilencingPuromycin0
(0)

TREK-2 siRNA (h)

sc-42347hGene SilencingN/A
1
(0)

TREK-2 shRNA Plasmid (h)

sc-42347-SHhGene SilencingPuromycin
1
(0)

TREK-2 shRNA (h) Lentiviral Particles

sc-42347-VhGene SilencingPuromycin
1
(0)

TREK-2 siRNA (m)

sc-42348mGene SilencingN/A0
(0)

TREK-2 shRNA Plasmid (m)

sc-42348-SHmGene SilencingPuromycin0
(0)

TREK-2 shRNA (m) Lentiviral Particles

sc-42348-VmGene SilencingPuromycin0
(0)