Date published: 2026-4-24

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IL-26 Activators

Interleukin-26 (IL-26) is a member of the interleukin family of cytokines that have defined roles in the immune response. These cytokines operate as signaling molecules, enabling communication between cells and directing cellular responses to environmental cues. IL-26, specifically, is associated with immune reactions, aiding in the orchestration of responses against various challenges.

The term IL-26 Activators refers to compounds that induce or augment the production or activity of IL-26. These activators can originate from various sources. Some are endogenous, like certain cytokines or cellular signals, that directly or indirectly influence the expression of IL-26. Others are exogenous, found in external agents such as microbial components. For instance, bacterial components like lipopolysaccharides have been shown to provoke immune responses and can impact the production of various cytokines. Similarly, some specific small molecules might interact with cellular pathways, leading to enhanced IL-26 expression. The response to these activators can vary based on the cellular environment, including the cell type and its activation state. Given the importance of IL-26 in immune signaling, understanding its regulation, including the impact of various activators, is crucial to the broader field of immunology.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Lipopolysaccharide, E. coli O55:B5

93572-42-0sc-221855
sc-221855A
sc-221855B
sc-221855C
10 mg
25 mg
100 mg
500 mg
$98.00
$171.00
$425.00
$1560.00
12
(2)

LPS is a potent activator of immune cells, inducing the production of various cytokines.

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$41.00
$132.00
$214.00
$500.00
$948.00
119
(6)

PMA is commonly used to activate protein kinase C, influencing cytokine production.

Ionomycin, free acid

56092-81-0sc-263405
sc-263405A
1 mg
5 mg
$96.00
$264.00
2
(2)

Ionomycin is a calcium ionophore that can synergize with PMA to activate immune cells.

Polyinosinic acid - polycytidylic acid sodium salt, double-stranded

42424-50-0sc-204854
sc-204854A
10 mg
100 mg
$139.00
$663.00
2
(1)

Mimics viral RNA and can induce cytokine production through TLR3.

2′,3′-cGAMP

1441190-66-4sc-507484
10 mg
$1800.00
(0)

An endogenous second messenger in the cGAS-STING pathway, known to activate immune responses.

R-848

144875-48-9sc-203231
sc-203231A
sc-203231B
sc-203231C
5 mg
25 mg
100 mg
500 mg
$102.00
$306.00
$510.00
$1559.00
12
(1)

An imidazoquinoline known to stimulate cytokine production via TLR7/TLR8.