Interleukin-26 (IL-26) is a member of the interleukin family of cytokines that have defined roles in the immune response. These cytokines operate as signaling molecules, enabling communication between cells and directing cellular responses to environmental cues. IL-26, specifically, is associated with immune reactions, aiding in the orchestration of responses against various challenges.
The term IL-26 Activators refers to compounds that induce or augment the production or activity of IL-26. These activators can originate from various sources. Some are endogenous, like certain cytokines or cellular signals, that directly or indirectly influence the expression of IL-26. Others are exogenous, found in external agents such as microbial components. For instance, bacterial components like lipopolysaccharides have been shown to provoke immune responses and can impact the production of various cytokines. Similarly, some specific small molecules might interact with cellular pathways, leading to enhanced IL-26 expression. The response to these activators can vary based on the cellular environment, including the cell type and its activation state. Given the importance of IL-26 in immune signaling, understanding its regulation, including the impact of various activators, is crucial to the broader field of immunology.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Lipopolysaccharide, E. coli O55:B5 | 93572-42-0 | sc-221855 sc-221855A sc-221855B sc-221855C | 10 mg 25 mg 100 mg 500 mg | $98.00 $171.00 $425.00 $1560.00 | 12 | |
LPS is a potent activator of immune cells, inducing the production of various cytokines. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA is commonly used to activate protein kinase C, influencing cytokine production. | ||||||
Ionomycin, free acid | 56092-81-0 | sc-263405 sc-263405A | 1 mg 5 mg | $96.00 $264.00 | 2 | |
Ionomycin is a calcium ionophore that can synergize with PMA to activate immune cells. | ||||||
Polyinosinic acid - polycytidylic acid sodium salt, double-stranded | 42424-50-0 | sc-204854 sc-204854A | 10 mg 100 mg | $139.00 $663.00 | 2 | |
Mimics viral RNA and can induce cytokine production through TLR3. | ||||||
2′,3′-cGAMP | 1441190-66-4 | sc-507484 | 10 mg | $1800.00 | ||
An endogenous second messenger in the cGAS-STING pathway, known to activate immune responses. | ||||||
R-848 | 144875-48-9 | sc-203231 sc-203231A sc-203231B sc-203231C | 5 mg 25 mg 100 mg 500 mg | $102.00 $306.00 $510.00 $1559.00 | 12 | |
An imidazoquinoline known to stimulate cytokine production via TLR7/TLR8. | ||||||