FDC-SP activators belong to a specific chemical class designed to modulate the function of FDC-SP, a protein or molecule with a particular role in biological systems. FDC-SP, which stands for Follicular Dendritic Cell-Secreted Protein, plays an important role within the immune system and lymphoid tissues. It is typically produced and secreted by follicular dendritic cells, specialized cells found in lymphoid follicles of secondary lymphoid organs like lymph nodes, spleen, and tonsils. The primary function of FDC-SP is related to its involvement in the formation and maintenance of germinal centers within lymphoid tissues. Germinal centers are critical for the development of adaptive immune responses, including the production of antibodies by B cells and the generation of memory B cells.
Activators of FDC-SP may influence the protein's secretion or function, potentially affecting the dynamics of germinal center formation and the immune response. Understanding how FDC-SP activators work and their effects on immune processes is a subject of interest in immunology research. These activators could provide insights into the regulation of immune responses and the development of strategies to enhance or modulate the immune system's activity when needed.
Nome del prodotto | CAS # | Codice del prodotto | Quantità | Prezzo | CITAZIONI | Valutazione |
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Lipopolysaccharide, E. coli O55:B5 | 93572-42-0 | sc-221855 sc-221855A sc-221855B sc-221855C | 10 mg 25 mg 100 mg 500 mg | $96.00 $166.00 $459.00 $1615.00 | 12 | |
Il lipopolisaccaride (LPS) è noto per indurre l'espressione di FDC-SP nelle cellule mononucleate del sangue periferico umano (PBMC). L'LPS funziona a concentrazioni che hanno dimostrato di indurre l'espressione di citochine e chemochine di tipo I, il che significa che è regolato da segnali di immunità innata. |