DSCR 5, also termed PIGP, has a defined role in the synthesis of glycosylphosphatidylinositol (GPI) anchors, which are essential for anchoring certain proteins to the cell surface. Several chemicals actively participate in or influence this biosynthetic pathway. Fundamental elements like mannose and glucosamine supply the initial sugar components, establishing the scaffold for subsequent GPI anchor development. Moreover, myo-inositol is indispensable for the creation of phosphatidylinositol, a precursor in the GPI synthesis process. Notably, arachidonic acid and palmitic acid play pivotal roles in forming the lipid moiety of GPI anchors, ensuring correct attachment to the membrane.
Phosphatidic acid, ethanolamine, and dolichol phosphate further delineate the intricacies of GPI synthesis, contributing to phosphatidylinositol formation, providing the ethanolamine moiety, and facilitating sugar transfers, respectively. On a broader spectrum, the complex interplay between ceramide and GPI-anchored proteins hints at the indirect influence ceramide can exert on proteins like DSCR 5. Sphingosine's role in ceramide structure in GPI synthesis reinforces the interconnected nature of these pathways. Furthermore, acetic acid's potential influence on acetylation processes associated with GPI-anchored proteins underscores the myriad ways in which different chemicals can impact DSCR 5 and its associated functions.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
D-Mannose | 3458-28-4 | sc-211180 sc-211180A | 100 g 250 g | $103.00 $161.00 | 1 | |
Essential sugar substrate for glycosylphosphatidylinositol (GPI) anchor synthesis. | ||||||
myo-Inositol | 87-89-8 | sc-202714 sc-202714A sc-202714B sc-202714C | 100 g 250 g 1 kg 5 kg | $80.00 $151.00 $275.00 $837.00 | ||
Crucial for the formation of phosphatidylinositol, a precursor in the GPI synthesis pathway. | ||||||
Arachidonic Acid (20:4, n-6) | 506-32-1 | sc-200770 sc-200770A sc-200770B | 100 mg 1 g 25 g | $92.00 $240.00 $4328.00 | 9 | |
Involved in the lipid moiety formation of GPI anchors. | ||||||
Phosphatidic Acid, Dipalmitoyl | 169051-60-9 | sc-201057 sc-201057B sc-201057A | 100 mg 250 mg 500 mg | $106.00 $244.00 $417.00 | ||
Contributes to the synthesis of phosphatidylinositol, which is vital for GPI synthesis. | ||||||
C2 Ceramide | 3102-57-6 | sc-201375 sc-201375A | 5 mg 25 mg | $124.00 $460.00 | 12 | |
Interacts with GPI anchors, indirectly affecting the function of proteins like DSCR 5. | ||||||
D-Glucosamine | 3416-24-8 | sc-278917A sc-278917 | 1 g 10 g | $201.00 $779.00 | ||
A component in the GPI anchor synthesis pathway, supplying the initial sugar moiety. | ||||||
Palmitic Acid | 57-10-3 | sc-203175 sc-203175A | 25 g 100 g | $114.00 $286.00 | 2 | |
Integral for the lipid tail formation of GPI anchors. | ||||||
Ethanolamine | 141-43-5 | sc-203042 sc-203042A sc-203042B | 25 ml 500 ml 2.5 L | $22.00 $56.00 $204.00 | 1 | |
Provides the ethanolamine moiety in GPI anchor synthesis. | ||||||
Acetic acid | 64-19-7 | sc-214462 sc-214462A | 500 ml 2.5 L | $63.00 $106.00 | 5 | |
May influence the acetylation processes associated with GPI-anchored proteins. | ||||||
D-erythro-Sphingosine | 123-78-4 | sc-3546 sc-3546A sc-3546B sc-3546C sc-3546D sc-3546E | 10 mg 25 mg 100 mg 1 g 5 g 10 g | $90.00 $194.00 $510.00 $2448.00 $9384.00 $15300.00 | 2 | |
Can contribute to the ceramide structure in the GPI anchor synthesis. | ||||||