Date published: 2026-4-24

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C22orf42 Activators

C22orf42 activators include compounds that can indirectly regulate the activity of the C22orf42 protein through various cellular signaling pathways. These compounds can modulate numerous aspects of cellular function, including gene expression, energy homeostasis, and protein synthesis. For instance, activators of AMPK, such as AICAR and Metformin, can trigger a cellular energy response, leading to alterations in the expression of genes that include metabolic regulators, and this may encompass C22orf42.

Additionally, compounds that influence chromatin structure and transcription factor activity, such as retinoic acid, HDAC inhibitors like sodium valproate, or SIRT1 activators like resveratrol, may cause broad changes in gene expression patterns. Likewise, molecules that impact signaling pathways associated with cellular growth, differentiation, and survival, such as mTOR inhibitors, could have indirect effects on C22orf42.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

AICAR

2627-69-2sc-200659
sc-200659A
sc-200659B
50 mg
250 mg
1 g
$65.00
$280.00
$400.00
48
(2)

AICAR activates AMP-activated protein kinase (AMPK), which can enhance cellular energy homeostasis. Activation of AMPK can lead to the transcriptional regulation of genes involved in metabolic processes, potentially including C22orf42.

Metformin-d6, Hydrochloride

1185166-01-1sc-218701
sc-218701A
sc-218701B
1 mg
5 mg
10 mg
$292.00
$822.00
$1540.00
1
(1)

Metformin is an activator of AMPK, leading to changes in gene expression and protein synthesis. This could theoretically include the expression of C22orf42 as part of a response to metabolic state.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

Retinoic acid modulates gene expression via retinoic acid receptors and could thus influence genes related to differentiation or development, which may include C22orf42.

Rolipram

61413-54-5sc-3563
sc-3563A
5 mg
50 mg
$77.00
$216.00
18
(1)

Rolipram inhibits phosphodiesterase 4, increasing cAMP levels, which could enhance the activity of PKA and influence gene transcription, possibly affecting C22orf42 expression.

SB 431542

301836-41-9sc-204265
sc-204265A
sc-204265B
1 mg
10 mg
25 mg
$82.00
$216.00
$416.00
48
(1)

SB 431542 inhibits the TGF-beta signaling pathway, which might lead to compensatory regulatory effects on other genes, potentially including C22orf42 as part of a complex regulatory network.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Curcumin affects multiple signaling pathways, including NF-kB, and could potentially alter the expression of genes involved in inflammation and stress responses, possibly including C22orf42.

Valproic Acid

99-66-1sc-213144
10 g
$87.00
9
(1)

Sodium valproate is an HDAC inhibitor, which can lead to chromatin remodeling and affect gene expression. It might influence the expression of C22orf42 by altering the acetylation status of histones.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

Resveratrol activates SIRT1, which can deacetylate histones and transcription factors, potentially affecting gene expression patterns including that of C22orf42.

Pioglitazone

111025-46-8sc-202289
sc-202289A
1 mg
5 mg
$55.00
$125.00
13
(1)

Pioglitazone activates PPAR-gamma, a nuclear receptor that regulates gene expression, potentially influencing C22orf42 in the context of metabolic regulation.

Dexamethasone

50-02-2sc-29059
sc-29059B
sc-29059A
100 mg
1 g
5 g
$91.00
$139.00
$374.00
36
(1)

Dexamethasone acts on glucocorticoid receptors to regulate gene expression. It might affect the expression of genes related to stress response, potentially including C22orf42.