β-defensin 125 Activators
These peptides are characterized by their structure, which typically includes a core of beta-sheet regions stabilized by disulfide bonds. This structure allows β-defensins to interact with and permeate the lipid membranes of pathogens, leading to their antimicrobial activity. Human β-defensins also possess immunomodulatory functions, such as recruiting immune cells to the site of infection and modulating cell signaling pathways involved in inflammation and immune responses.β-defensins are predominantly expressed in epithelial tissues that interface with the external environment, including the skin, respiratory, gastrointestinal, and urogenital tracts. This strategic expression pattern enables them to respond rapidly to microbial invasion at these critical barriers.
The expression of β-defensins can be induced by the presence of bacteria and other pathogens, as well as by cytokines and inflammatory mediators. This inducible nature allows for a rapid and localized increase in peptide concentration at infection sites, enhancing the body's ability to combat infectious agents.Should "β-defensin 125" be a member of this family, it would be expected to share these defining antimicrobial and immunomodulatory properties, contributing to the host's protective mechanisms against a wide array of pathogens.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $71.00 $163.00 $296.00 | 2 | |
Vitamin D3 can enhance the expression of antimicrobial peptides including β-defensins through the Vitamin D receptor (VDR) pathway. | ||||||
Butyric acid | 107-92-6 | sc-214640 sc-214640A | 1 kg 10 kg | $64.00 $177.00 | ||
Butyrate, a short-chain fatty acid produced by gut microbiota, can upregulate defensin expression in the gut epithelium. | ||||||
1α,25-Dihydroxyvitamin D3 | 32222-06-3 | sc-202877B sc-202877A sc-202877C sc-202877D sc-202877 | 50 µg 1 mg 5 mg 10 mg 100 µg | $220.00 $645.00 $1000.00 $1500.00 $440.00 | 32 | |
The active form of Vitamin D, it plays a role in stimulating the immune system and can upregulate β-defensin expression. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid, derived from Vitamin A, influences immune responses and may enhance β-defensin expression. | ||||||
Lipopolysaccharide, E. coli O55:B5 | 93572-42-0 | sc-221855 sc-221855A sc-221855B sc-221855C | 10 mg 25 mg 100 mg 500 mg | $98.00 $171.00 $425.00 $1560.00 | 12 | |
LPS, a component of the outer membrane of Gram-negative bacteria, can induce β-defensin expression as part of the immune response. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Zinc is crucial for immune function and has been shown to influence the expression of various defensins. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol, a polyphenol, can modulate immune responses and potentially upregulate β-defensin expression. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin has anti-inflammatory properties and might influence the expression of antimicrobial peptides including β-defensins. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG, found in green tea, possesses anti-inflammatory properties and may affect β-defensin expression. | ||||||
Lactoferrin | 146897-68-9 | sc-394420 sc-394420A sc-394420B sc-394420C | 10 mg 50 mg 100 mg 1 g | $122.00 $408.00 $580.00 $1494.00 | ||
Lactoferrin, a component of the innate immune system, can modulate immune responses and potentially β-defensin expression. | ||||||