Anticorps WHIP (A-7): sc-271637
- L'Anticorps WHIP (A-7) est un monoclonal de souris IgG1 (chaîne légère kappa) fourni en 200 µg/ml
- dirigé contre les acides aminés 366-665 situés au niveau C-terminus de WHIP d'origine human
- recommandé pour la détection de WHIP d'origine mouse, rat et human par WB, IP, IF, IHC(P) et ELISA
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP et m-IgGκ BP-HRP sont les réactifs secondaires recommandés pour la détection de l'anticorps WHIP (A-7) pour des applications de WB and IHC(P). Ces réactifs sont maintenant proposés en kit avec l'anticorps WHIP (A-7) (voir Informations pour la commande ci-dessous).
ACCÈS RAPIDE AUX LIENS
VOIR ÉGALEMENT...
Werner's syndrome is an inherited, autosomal recessive disorder that is characterized by premature aging and commonly results in cancer. WHIP, also known as WRNIP1 (Werner helicase-interacting protein 1) is a ubiquitously expressed member of the AAA ATPase family that is involved in the regulation of DNA synthesis. Localized to the nucleus, WHIP acts as a modulator for initiation events during DNA polymerase-mediated DNA synthesis and, through its ATPase activity, can detect DNA damage or arrested replication forks. WHIP is found in granular structures within the nucleus, where it interacts with the N-terminal domain of WRN, the protein product of the gene responsible for Werner's syndrome. Due to its close association with WRN, WHIP is thought to be involved in the aging process and thus may play a role in the development of Werner's syndrome. Four isoforms of WHIP are produced due to alternative splicing events.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps WHIP (A-7) | sc-271637 | 200 µg/ml | $316.00 | |||
WHIP (A-7): m-IgG Fc BP-HRP Kit | sc-537669 | 200 µg Ab; 10 µg BP | $354.00 | |||
WHIP (A-7): m-IgGκ BP-HRP Kit | sc-535010 | 200 µg Ab; 40 µg BP | $354.00 | |||
WHIP (A-7): m-IgG1 BP-HRP Kit | sc-545295 | 200 µg Ab; 20 µg BP | $354.00 |