WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids, which commonly form a tertiary propeller structure. While proteins that contain WD-repeats participate in a wide range of cellular functions, they are generally involved in regulatory mechanisms involving signal transduction, apoptosis, transcriptional regulation, cell cycle control. WD repeats serve as sites for protein-protein interaction and some seem to mediate the assembly of protein complexes. With 11 WD repeats, WDR1 (WD repeat domain 1), also known as AIP1 or NORI-1, is a 606 amino acid protein that localizes to the cytoskeleton and is a member of the WD repeat AIP1 family. Existing as two alternatively spliced isoforms, WDR1 induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins.
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Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps WDR1 (B-8) | sc-393130 | 200 µg/ml | $316.00 | |||
WDR1 (B-8): m-IgG Fc BP-HRP Kit | sc-538147 | 200 µg Ab; 10 µg BP | $354.00 | |||
WDR1 (B-8): m-IgGκ BP-HRP Kit | sc-535707 | 200 µg Ab; 40 µg BP | $354.00 | |||
WDR1 (B-8): m-IgG1 BP-HRP Kit | sc-545547 | 200 µg Ab; 20 µg BP | $354.00 |