Anticorps ULBP4 (C-11): sc-390784
- L'Anticorps ULBP4 (C-11) est un monoclonal de souris IgG2b κ, cité dans 1 publications, fourni en 200 µg/ml
- dirigé contre les acides aminés 40-118 dans une région interne de ULBP4 d'origine human
- recommandé pour la détection de ULBP4 d'origine human par WB, IP, IF, IHC(P) et ELISA
- Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire ULBP4 (C-11). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.
The immune system contains genetically encoded subsystems, which monitor the extracellular environment in order to eliminate pathogens and resolve abnormal or transformed tissues. Cytomegalovirus UL16 binding proteins, known as ULBPs, are GPI-linked glycoproteins that belong to the extended MHC class I family and are distantly related to MHC class I polypeptide-related sequence B, known as MICB. ULBP and MICB proteins are ligands for the activating receptor NKG2D/DAP10, which causes lymphocyte activation resulting in the secretion of cytokines, such as interferon-gamma, and tumor cell lysis. The interaction of ULBP or MICB with NKG2D/DAP10 can be blocked by the soluble form of UL16. ULBPs stimulate cytokine and chemokine production from NK cells, CD8 alpha/beta T cells, and gamma/delta T cells. Soluble forms of ULBPs induce protein tyrosine phosphorylation and activation of the Janus kinase 2, STAT5, extracellular signal-regulated kinase, mitogen-activated protein kinase and phosphatidylinositol 3-kinase (PI 3-kinase)/Akt signal transduction pathways.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps ULBP4 (C-11) | sc-390784 | 200 µg/ml | $316.00 |