Anticorps UBC12 (L-34): sc-100608
- L'Anticorps UBC12 (L-34) est un monoclonal de souris IgG1 κ, cité dans 3 publications, fourni en 100 µg/ml
- dirigé contre la UBC12 recombinante d'origine human
- recommandé pour la détection de UBC12 d'origine human par WB, IP, IF et ELISA
- Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire UBC12 (L-34). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.
Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). UBC12, also known as UBE2M (ubiquitin-conjugating enzyme E2M), hUbc12 or UBC-RS2, is a 183 amino acid member of the E2 ubiquitin-conjugating enzyme family. UBC12 is linked with NEDD8 (neural precursor cell expressed, developmentally down-regulated 8), a ubiquitin-like protein. Via this interaction, UBC12 facilitates the attachment of NEDD8 to proteins targeted for degradation. Due to its ability to control the conjugation of NEDD8 to cellular proteins, UBC12 is thought to play a role in cell proliferation events.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps UBC12 (L-34) | sc-100608 | 100 µg/ml | $333.00 |