Date published: 2025-9-9

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Anticorps TTI1 (H-1): sc-271638

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Fiches techniques
  • L'Anticorps TTI1 (H-1) est un monoclonal de souris IgG1 κ, cité dans 2 publications, fourni en 200 µg/ml
  • dirigé contre les acides aminés 1-300 situés au niveau N-terminus de TTI1 d'origine human
  • recommandé pour la détection de TTI1 d'origine mouse, rat et human par WB, IP, IF et ELISA
  • m-IgG Fc BP-HRP, 1 BP-HRP">m-IgG1 BP-HRP et m-IgGκ BP-HRP sont les réactifs de détection secondaire préférés pour l'anticorps TTI1 (H-1) pour les applications WB. Ces réactifs sont désormais proposés en lots avec l'anticorps TTI1 (H-1)(voir les informations de commande ci-dessous).

ACCÈS RAPIDE AUX LIENS

VOIR ÉGALEMENT...

TTI1 (TELO2-interacting protein 1 homolog), also known as SMG10, is a 1,089 amino acid protein that is widely expressed and belongs to the TTI1 family. TTI1 functions as a regulator of the DNA damage response (DDR) and is a component of the TTT complex, which is necessary for the stabilization of protein levels of the phosphatidylinositol 3-kinase (PIKK) family. The TTT complex is a part of the cellular resistance to DNA damage stresses such as ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). In combination with the TTT complex and HSP90, TTI1 may play a role in the proper folding of newly synthesized PIKKs. TTI1 also is involved in the assembly of mTORC1 and mTORC2 complexes, as well as their stabilization and maintenance. TTI1 is post-tanslationally modified at serine 459 and the gene encoding this protein maps to human chromosome 20.

Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

Informations pour la commande

Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

Anticorps TTI1 (H-1)

sc-271638
200 µg/ml
$316.00

TTI1 (H-1): m-IgG Fc BP-HRP Kit

sc-537670
200 µg Ab; 10 µg BP
$354.00

TTI1 (H-1): m-IgGκ BP-HRP Kit

sc-535011
200 µg Ab; 40 µg BP
$354.00

TTI1 (H-1): m-IgG1 BP-HRP Kit

sc-545296
200 µg Ab; 20 µg BP
$354.00

What is the recommended fixation method for immunofluorescence staining with TTI1 (H-1): sc-271638 monoclonal antibody?

Posée par: Germaine
Thank you for your inquiry. We recommend fixing cells for 5 minutes in -10°C methanol and allowing to air dry. The full protocol can be viewed here: https://www.scbt.com/scbt/resources/protocols/immunofluorescence-cell-staining
Répondue par: Technical Support
Date de publication: 2017-02-27
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Rated 5 de 5 de par Produced exceptional immunofluorescence cytoplasmicProduced exceptional immunofluorescence cytoplasmic staining in methanol-fixed HeLa cells. -SCBT QC
Date de publication: 2015-02-07
Rated 5 de 5 de par Nice Western Blot data of TTI1 expression in nonNice Western Blot data of TTI1 expression in non-transfected and human TTI1 transfected 293 whole cell lysates. -SCBT QC
Date de publication: 2013-09-08
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Anticorps TTI1 (H-1) est évalué 5.0 de 5 de 2.
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