ACCÈS RAPIDE AUX LIENS
VOIR ÉGALEMENT...
Tastin (trophinin associated protein), also known as TROAP, is essential for centrosome integrity and proper bipolar organization of spindle assembly during mitosis. It is expressed at high levels in bone marrow, testis, and thymus, localizing to the cytoplasm and associating with microtubules, the mitotic spindle and centrosomes. Tastin expression peaks in the cell during the G2/M phase and declines after the cell divides. Cells overexpresssing Tastin form monopolar spindles, while cells depleted of Tastin form multipolar spindles. Tastin binds directly to the Dynein light chain (Dynein LC or Tctex-1) and γ Tubulin, further supporting its role in spindle assembly and cell proliferation. In addition, Tastin can interact with and form a complex with Bystin and Trophinin, facilitating cell adhesion and, in particular, embryo implantation.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Tastin (F-12) | sc-271716 | 200 µg/ml | $316.00 | |||
Tastin (F-12): m-IgG Fc BP-HRP Kit | sc-537686 | 200 µg Ab; 10 µg BP | $354.00 | |||
Tastin (F-12): m-IgGκ BP-HRP Kit | sc-535032 | 200 µg Ab; 40 µg BP | $354.00 | |||
Tastin (F-12): m-IgG1 BP-HRP Kit | sc-545306 | 200 µg Ab; 20 µg BP | $354.00 | |||
Tastin (F-12) peptide neutralisant | sc-271716 P | 100 µg/0.5 ml | $68.00 |