ACCÈS RAPIDE AUX LIENS
VOIR ÉGALEMENT...
U1, U2, U5 and U4/U6 are small nuclear ribonucleoproteins (snRNPs) that comprise the spliceosome in eukaryotes. Each UsnRNP contains common Sm proteins B/B′, D1, D2, D3, E, F and G. The Sm proteins pair up as D1-D2, B/B′-D3 and E-F-G to form RNA-free hetero-oligomers in the cytoplasm. Sm proteins aid in the cytoplasmic construction of the UsnRNPs by binding to a conserved Sm site on UsnRNA and forming a stable snRNP core complex. Sm F (also known as SNRPF for small nuclear ribonucleoprotein polypeptide F) and Sm G (also known as SNRPG) are both expressed as 0.5 kb transcripts in HeLa cells. The genes encoding human Sm F and Sm G map to chromosomes 12 and 2, respectively. Sm proteins are often targeted by autoantibodies produced in patients suffering from systemic lupus erythematosus (SLE). One class of these autoantibodies react specifically with native Sm E-F-G complexes.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Sm G (K-15) | sc-101150 | 100 µg/ml | $333.00 |